Differential expression of βig-h3 in human hepatoma cell lines

郭卫平; 周宏伟; 蒋建利; 张洪新

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Differential expression of βig-h3 in human hepatoma cell lines

Updated：2026-03-12

- Differential expression of βig-h3 in human hepatoma cell lines
- Differential expression of βig-h3 in human hepatoma cell lines
- 解放军医学杂志（英文版） 2007年第1期页码：8-11
- Affiliations：
  
  1. Department of Interventional Radiation Tangdu Hospital
  2. Fourth Military Medical University
  3. ,Xi’an,710033
  4. Cell Engineering Research Centre
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China （No. 30200144）
- DOI：
  中图分类号： R735.7
- 纸质出版：2007
- Accepted：
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Differential expression of βig-h3 in human hepatoma cell lines[J]. 解放军医学杂志（英文版）, 2007,(1):8-11.

[1]郭卫平,周宏伟,蒋建利,张洪新.Differential expression of βig-h3 in human hepatoma cell lines[J].Journal of Medical Colleges of PLA,2007(01):8-11.
Differential expression of βig-h3 in human hepatoma cell lines[J]. 解放军医学杂志（英文版）, 2007,(1):8-11. DOI：

[1]郭卫平,周宏伟,蒋建利,张洪新.Differential expression of βig-h3 in human hepatoma cell lines[J].Journal of Medical Colleges of PLA,2007(01):8-11. DOI：

摘要

Abstract

<正>Objective:To observe the differential expression of TGF-β-induced gene human clone 3 （βig-h3） in human hepatoma cell lines. Methods: Human hepatoma cells HHCC. 7721. T7721 constructed by stably transfecting HAbl8G/CD147 cDNA into 7721 and normal human liver cell QZG were cultured as previously. RT-PCR and western blot were used to investigate the differential expression ofβig-h3 in human hepatoma cell lines and normal liver cell. Results:The results of RT-PCR suggested that the expression ofβig-h3 mRNA in human hepatoma cells was higher than that in normal human liver cell QZG（P< 0. 01）

and its expression level in human hepatoma cells in turn was HHCC>T7721>7721. Moreover

the similar results ofβig-h.3 protein expression were testified by western blot. Conclusion: This study demonstrates that the expression ofβig-h3 in hepatoma cell lines is higher than that in normal liver cell QZG

which provides a sound basis for exploring the function ofβig-h3 in processes of adhesion and metastasis of human hepatoma cells.

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