Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells

于春水; 谭升顺; 眭维耻; 郗彦萍

Your Location：

Home >

Browse articles >

Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells

Updated：2026-03-12

- Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells
- Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells
- 解放军医学杂志（英文版） 2006年第6期页码：375-378
- Affiliations：
  
  1. Department of Dermatology Second Affiliated Hospital Medical School of Xi’an Jiaotong University
  2. Department of Dermatology Affiliated Hospital of North Sichuan Medical College
  3. ,China
  4. Nanchong,637000
- Author bio：
- Funds：
  
  Supported by the Shaanxi Youth Science Fund （No.2003K10-G56）
- DOI：
  中图分类号： Q75
- 纸质出版：2006
- Accepted：
Scan QR Code
Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells[J]. 解放军医学杂志（英文版）, 2006,(6):375-378.

[1]于春水,谭升顺,眭维耻,郗彦萍.Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells[J].Journal of Medical Colleges of PLA,2006(06):375-378.
Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells[J]. 解放军医学杂志（英文版）, 2006,(6):375-378. DOI：

[1]于春水,谭升顺,眭维耻,郗彦萍.Effects of different doses of acitretin on FGF10 mRNA transcription and its protein translation in HaCaT cells[J].Journal of Medical Colleges of PLA,2006(06):375-378. DOI：

摘要

Abstract

<正>Objective:To observe the effects of different doses of acitretin on the transcription of FGF10 mRNA and the translation of FGF10 protein in cultured HaCaT cells. Methods: HaCaT cells were treated with different doses of acitretin for 48 h

then the changes on the transcription of FGFfO mRNA and the translation of FGF10 protein in these cells were detected by immunofluorescence and in situ hybridization assay. Results: Compared with the control group

the transcription of FGF10 mRNA and the translation of FGF10 protein were gradually decreased along with the increasing dose of acitretin. There were significant differences between different groups （P<0. 01）. Conclusion: Acitretin could inhibit the transcription of FGF10 mRNA and the translation of FGF10 protein in HaCaT cells. With the dose of acitretin increased

the stains of both FGF10 mRNA and FGF10 protein in HaCaT cells are reduced.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据