Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue

袁红斌; 何星颖; 徐海涛; 朱秋峰; 王亚华; 石学银

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Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue

Updated：2026-03-12

- Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue
- Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue
- 解放军医学杂志（英文版） 2006年第6期页码：397-400
- Affiliations：
  
  1. Department of Anesthesiology Changzheng Hospital Second Military Medical University
  2. ,China
- Author bio：
- Funds：
  
  Supported by Science and Research Foundation of Shanghai Municipal Health Bureau （200537103）
- DOI：
  中图分类号： R684
- 纸质出版：2006
- Accepted：
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Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue[J]. 解放军医学杂志（英文版）, 2006,(6):397-400.

[1]袁红斌,何星颖,徐海涛,朱秋峰,王亚华,石学银.Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue[J].Journal of Medical Colleges of PLA,2006(06):397-400.
Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue[J]. 解放军医学杂志（英文版）, 2006,(6):397-400. DOI：

[1]袁红斌,何星颖,徐海涛,朱秋峰,王亚华,石学银.Expression of mu-opioid receptors in human chronic inflamed knee joint synovium tissue[J].Journal of Medical Colleges of PLA,2006(06):397-400. DOI：

摘要

Abstract

<正>Objective: To examine the changes of mu-opioid receptors （MORs） expression in human chronic inflamed knee joint synovium tissue. Methods:Knee joint synovium tissues were taken from 21 patients with chronic arthritis （inflamed group） and 6 fresh bodies with normal knee joints （control group）. And the expression of MORs was detected by using immunohistochemistry. flow cytometry（FCM） and reverse-transcription polymerase chain reaction （RT-PCR）. Results: The expression of MORs in the inflamed group was significantly higher than that in the normal group by using the 3 techniques（P<0. 05）. Conclusion: Chronic inflammation enhances the up-regulation of MORs in human knee joint synovium tissue.

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