<正>Objective:To explore the characteristic of operation

intra-operation treatment and the application of immunosuppressant in pediatric renal transplantation in order to improve therapeutic effectiveness.Methods:From March 1986 to October 2006

the clinical data of 63 children who underwent renal transplantation in our hospital were retrospectively analyzed.Results:The 1-

3-

5-

10-year graft survival rates were 98.4%

90.5%

88.9% and 68.3%

respectively.And the corresponding patient survival rates were 100%

95.2%

92.1%

71.4%.The body weight increased 4 to 12 kg and the body height grew up 2 to 6 cm during the first year post-transplantation.The main complications in the first year post-transplantation were hypertension（26/63

41.3%）

crinosity（14/63

22.2%）

drug-induced hepatic injury（11/63

17.5%）

gingival hyperplasia（10/63

15.8%）

pulmonary infection（9/63

14.3%）

bone marrow suppression（5/63

7.9%）

herpes（4/63

6.3%）and diabetes（3/63

4.8%）.Conclusion:Renal transplantation is a preferred method for the treatment of children in end-stage renal disease（ESRD）.Good tissue matching

proper operative time and pattern

peri-operactive care were essential to success

as well as appropriate immuno-suppressant strategy and good compliance.