Nonpeptide somatostatin analogs:recent advances in its application and research

Wang Song1; Liang Qingmo1; Liao Duanfang2 1Department of Oncological Surgery; Nanhua Hospital; University of South China; Hengyang421002; Hunan; China2Institute of Pharmacy and Pharmacology; University of South China; Hengyang 421001; Hunan; China

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Nonpeptide somatostatin analogs:recent advances in its application and research

Updated：2026-03-12

- Nonpeptide somatostatin analogs:recent advances in its application and research
- Nonpeptide somatostatin analogs:recent advances in its application and research
- 解放军医学杂志（英文版） 2008年23卷第6期页码：364-376
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  中图分类号： R977.1
- 纸质出版：2008
- Accepted：
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Nonpeptide somatostatin analogs:recent advances in its application and research[J]. 解放军医学杂志（英文版）, 2008,23(6):364-376.

[1].Nonpeptide somatostatin analogs:recent advances in its application and research[J].Journal of Medical Colleges of PLA,2008,23(06):364-376.
Nonpeptide somatostatin analogs:recent advances in its application and research[J]. 解放军医学杂志（英文版）, 2008,23(6):364-376. DOI：

[1].Nonpeptide somatostatin analogs:recent advances in its application and research[J].Journal of Medical Colleges of PLA,2008,23(06):364-376. DOI：

摘要

Abstract

Along with its wide anatomical distribution

somatostatin （SST） acts on multiple targets via a family of 5 receptors to produce a broad spectrum of biological effects. Therefore

a variety of peptide analogs have been produced and are widely used in clinical treatment. However

because of their flaws in the structure of peptide

the clinical efficacy is limited. In this review

we summarize the structure

pharmacological effects and the potential clinical value of non-peptide SST analogs. We focus on the research and development of non-peptide SST analogs since 1998

and discuss the problems and potential prospects for non-peptide SST analogs. We believe that as more non-peptide somatostatin analogs are successfully developed

the extensive clinical application of SSTs will contribute a great deal to medical science.

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