Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report

Ouyang Guifang; Zhu Huiling; Hong Yongwei; Xu Kaihong; Mu Qitian; Le Jing; Wu Wenmiao; Lu Ying; Gu Xuewei; Ni Lifeng Department of Hematology; the First People’s Hospital of Ningbo; Affiliated Medical College of Ningbo University; Ningbo 315010; China

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Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report

Updated：2026-03-12

- Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report
- Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report
- 解放军医学杂志（英文版） 2010年25卷第1期页码：54-57
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  中图分类号： R733.7
- 纸质出版：2010
- Accepted：
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Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report[J]. 解放军医学杂志（英文版）, 2010,25(1):54-57.

[1].Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report[J].Journal of Medical Colleges of PLA,2010,25(01):54-57.
Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report[J]. 解放军医学杂志（英文版）, 2010,25(1):54-57. DOI：

[1].Haploidentical stem cell transplantation used in treating primary plasma cell leukemia: a case report[J].Journal of Medical Colleges of PLA,2010,25(01):54-57. DOI：

摘要

Abstract

Here we report a successful protocol in treatment of a patient with primary plasma cell leukemia （PPCL） using haploidentical stem cell transplantation （hi-HSCT）. During first complete remission after routine chemotherapy

the patient received autologous blood stem cell transplantation

but he had relapse later. He gained a second CR after chemotherapy and underwent hi-HSCT from his daughter

who had HLA mismatched at three loci. Recovery of hemopoiesis was found at day 14 and complete donor chimerism was confirmed by PCR-STR on day 34

95 and 238. The patients have survived disease-free for 56 months since hi-HSCT

without serious graft-versus-host-disease.

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