Objective: To evaluate the outcomes of selective uterine artery embolization （SUAE） in treatment of symptomatic uterine fibroids using Color Doppler ultrasonography （CDUS）. Methods: As the procedure SUAE for fibroids

prospective data of the initial 65 consecutive women treated from March 2007 to September 2009 were collected. The follow-up period from 1 week to 30 months

using questionnaires

we investigated the fibroid-related physical and psychological symptoms

and the cumulative rates of symptom control

gynecologic interventions

and complications. The volumes of uterine and uterine fibroids were calculated by CDUS pre- and post-SUAE for 6 months. And we tested the levels of internal hormone including FSH

LH and E2 before and after SUAE for 3

6 months. Results: SUAE was performed successfully in all patients. There was no peri-operative morbidity in all procedures. Compared with pre-SUAE volumes of uterine [（322±112） cm3] and uterine fibroids [（125±46） cm3]

their volumes in post-SUAE were （144±72） cm3 and （51±11） cm3 （P<0.01）

and reduction rate was 58% and 61%

respectively. At 3

6 months after SUAE

levels of FSH

LH

and E2 were not decreased than that of in pre-SUAE （P>0.05）. After SUAE for 24 months

the fibroids related physical and psychological symptoms such as bleeding

pain and quality of life were significantly improved （P<0.01）. 90.8% （59/65） women had resolution of symptoms and no significant post-procedural symptoms. Parts of patients discharge necrotic fibroids. 86% （34/40） complications were minor

requiring no therapy. 9.2% （6/65） had significant post-procedural symptoms

requiring therapy in hospital or out-patient department. Conclusion: SUAE contributes to a long-term significant improvement of all investigated uterine fibroid-related symptoms and markedly improves women’s health-related quality of life. SUAE that no impair on changes of internal hormone

under suitable conditions

represents an attractive alternative to hysterectomy for the treatment of symptomatic fibroids and is a minimally invasive

new method of good clinical prognosis. CDUS is an effective to investigate the outcome of SUAE.