Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women

Liang Xiaoyan1; Chen Xiong2; Zuo Wanxing1; He Junlin3 1 Department of Obstetrics and Gynecology; Shanghai First People’s Hospital Baoshan Branch; Shanghai 200940; China; 2Department of Obstetrics and Gynecology; Changhai Hospital; Second Military Medical University; Shanghai 200433; 3Laboratory of Reproductive Biology; Department of Genetics; Chongqing Medical University; Chongqing 400016

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Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women

Updated：2026-03-12

- Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women
- Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women
- 解放军医学杂志（英文版） 2009年24卷第6期页码：329-336
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  中图分类号： R394
- 纸质出版：2009
- Accepted：
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Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women[J]. 解放军医学杂志（英文版）, 2009,24(6):329-336.

[1].Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women[J].Journal of Medical Colleges of PLA,2009,24(06):329-336.
Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women[J]. 解放军医学杂志（英文版）, 2009,24(6):329-336. DOI：

[1].Genetic imprinted gene PEG10 expression in deciduas of normal early pregnant women[J].Journal of Medical Colleges of PLA,2009,24(06):329-336. DOI：

摘要

Abstract

Objective: To investigate the role and significance of paternally expressed gene 10 （PEG10） in deciduas of normal pregnant women. Methods: Sixty deciduas tissue from pregnant 6 to 11 weeks were divided into six groups and in each group ten samples were done every gestational week. The expression and distribution of PEG10 in deciduas were examined by RT-PCR

hybridization in situ

Western Blot and laser scanning confocal microscopy. Results: The PEG10 mRNA and protein were expressed in deciduas tissue from pregnant 6 to 11 weeks. Among them

the expression of PEG10 showed a gradual increase as the pregnancy weeks increased. In RT-PCR

the PEG10 expression was lower at pregnant 6th week （0.6743±0.114）

from pregnant 7 to 8 weeks

the expression was increased gradually （7th week 0.7349±0.0083） and reached the pinnacle at 8th week （0.7354±0.0074）. And then the pinnacle began to descend （9th week 0.6340±0.0084

10th week 0.5901±0.0089 and 11th week 0.5261±0.0112）. There was a significant difference in the expression of PEG10 from pregnant 6 to 11 weeks except 7th week and 8th week. This expression characteristic was demonstrated by hybridization in situ. The similar conclusion was proved by Western Blot and laser scanning confocal microscopy. Conclusion: Expression of PEG10 may play an important role in early pregnancy.

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