Objective:To study the clinical value of Technetium-99m sestamibi myocardial perfusion single photon emission computed tomography（SPECT） in diabetes with suspected coronary artery diseases.Methods:Seventy-eight diabetic patients complicated with cardiac symptoms or electrocardiogram（ECG） abnormalities and suspected coronary heart disease hospitalized in the department of endocrinology from January

2008 to December

2008 were investigated.Technetium-99m sestamibi myocardial perfusion SPECT was performed in all patients.Exercise stress test was done in 35 cases（group A）.Adenosine stress test was done in 43 cases（group B）.Results:The positive rates in the two groups were 54.29%（19/35） and 53.48%（23/43）

respectively.There was no statistic difference between the 2 groups（P>0.05）.The abnormality rates in male and female groups were 63.04% and 28.13%

respectively（P<0.01）.Eighty-six segments of perfusion abnormality were detected in 38 positive patients.Four segments of fixed defect were found in 4 cases.Conclusion:As non-invasive method

myocardial perfusion SPECT can play an important role in the treatment of diabetes with suspected coronary artery disease.