Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells
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Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells
Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells
解放军医学杂志(英文版)2011年26卷第5期 页码:254-263
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Supported by the National Natural Science Foundation of China(30801238)
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中图分类号:R711.74
纸质出版:2011
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Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells[J]. 解放军医学杂志(英文版), 2011,26(5):254-263.
[1].Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells[J].Journal of Medical Colleges of PLA,2011,26(05):254-263.
Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells[J]. 解放军医学杂志(英文版), 2011,26(5):254-263.DOI:
[1].Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells[J].Journal of Medical Colleges of PLA,2011,26(05):254-263.DOI:
Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem cells
摘要
Abstract
The purpose of this study was to explore the change of telomerase in passage from human endometrial stromal stem cells isolated from human endometrium.Telomerase activity of cultured endometrial stromal cells was assessed at mRNA and protein levels using RT-PCR and immunohistochemistry technique.Telomerase mRNA and protein levels were higher at early passages
and then had a gradually decreased trend of immunoreactive intensity and gradually weakened positive cells with progressive passage in endometrial stromal stem cells.These results suggest that telomerase is contributed to the insenecence of endometrial stem cell.
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