Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures

YUAN Hengfeng; XU Weidong

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Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures

Updated：2026-03-12

- Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures
- Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures
- 解放军医学杂志（英文版） 2013年28卷第2期页码：113-119
- Affiliations：
  
  Department of Orthopedics,Changhai Hospital,Second Military Medical University
- Author bio：
- Funds：
- DOI：
  中图分类号： R687.4
- 纸质出版：2013
- Accepted：
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Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures[J]. 解放军医学杂志（英文版）, 2013,28(2):113-119.

[1]YUAN Hengfeng,XU Weidong.Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures[J].Journal of Medical Colleges of PLA,2013,28(02):113-119.
Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures[J]. 解放军医学杂志（英文版）, 2013,28(2):113-119. DOI：

[1]YUAN Hengfeng,XU Weidong.Heparin-induced thrombocytopenia associated with pulmonary embolism after total knee arthroplasty:a case report and review of literatures[J].Journal of Medical Colleges of PLA,2013,28(02):113-119. DOI：

摘要

Abstract

Type Ⅱ heparin-induced thrombocytopenia （HIT） is a life-threatening adverse drug reaction initiated by heparin administration. We described a rare case of LMWH-induced HIT complicated with proven pulmonary embolism （PE） in a 75-year-old male patient who hospitalized with diagnose of right knee osteoarthritis and was underwent total knee arthroplasty. The patient was successfully treated with argatroban. Early recognition and timely alternative therapy are of great importance in the treatment of this severe disorder.

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