Gastrointestinal problems in modern wars: clinical features and possible mechanisms

Wei-Feng Wang; Xiao-Xu Guo; Yun-Sheng Yang

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Gastrointestinal problems in modern wars: clinical features and possible mechanisms

PERSPECRTIVE | Updated：2022-12-27

- Gastrointestinal problems in modern wars: clinical features and possible mechanisms
- Gastrointestinal problems in modern wars: clinical features and possible mechanisms
- MMR 2015年2卷第2期页码：69-77
- Affiliations：
  
  Department of Gastroenterology and Hepatology, General Hospitalof PLA, Beijing 100853 China
- Author bio：
  
  *: userry282@aol.com
- Funds：
- DOI：
  中图分类号：
- 纸质出版：2015-06
- Accepted：
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Gastrointestinal problems in modern wars: clinical features and possible mechanisms[J]. MMR, 2015,2(2):69-77.

Wei-Feng Wang, Xiao-Xu Guo, Yun-Sheng Yang. Gastrointestinal problems in modern wars: clinical features and possible mechanisms[J]. Military Medical Research, 2015, 2(2): 69-77.
Gastrointestinal problems in modern wars: clinical features and possible mechanisms[J]. MMR, 2015,2(2):69-77. DOI：

Wei-Feng Wang, Xiao-Xu Guo, Yun-Sheng Yang. Gastrointestinal problems in modern wars: clinical features and possible mechanisms[J]. Military Medical Research, 2015, 2(2): 69-77. DOI：

摘要

Abstract

Gastrointestinal problems are common during wars

and they have exerted significant adverse effects on the health of service members involved in warfare. The spectrum of digestive diseases has varied during wars of different eras. At the end of the 20th century

new frontiers of military medical research emerged due to the occurrence of high-tech wars such as the Gulf War and the Kosovo War

in which ground combat was no longer the primary method of field operations. The risk to the military personnel who face trauma has been greatly reduced

but disease and non-battle injuries (DNBIs) such as neuropsychological disorders and digestive diseases seemed to be increased. Data revealed that gastrointestinal symptoms such as constipation

diarrhea

dyspepsia

and noncardiac chest pain are common among military personnel during modern wars. In addition

a large number of deployed soldiers and veterans who participated in recent wars presented with chronic gastrointestinal complaints

which fulfilled with the Rome III criteria for functional gastrointestinal disorders (FGIDs). It was also noted that many veterans who returned from the Gulf War suffered not only from chronic digestive symptoms but also from neuropsychological dysfunction; however

they also showed symptoms of other systems. Presently

this broad range of unexplained symptoms is known as "Gulf War syndrome" . The mechanism that underlies Gulf War syndrome remains unclear

but many factors have been associated with this syndrome such as war trauma

stress

infections

immune dysfunction

radiological factors

anthrax vaccination and so on. Some have questioned if the diagnosis of FGIDs can be reached given the complexity of the military situation. As a result

further studies are needed to elucidate the pathogenesis of gastrointestinal disease among military personnel.

关键词

Keywords

references

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