1.Wilmer Eye Institute at Johns Hopkins Hospital, Baltimore, Maryland, USA
2.Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA
3.Director of Informatics and Information Management, Vision Center of Excellence [VCE], Office of the Assistant Secretary of Defense for Health Affairs [ASD-HA], United States Department of Defense [DOD], Walter Reed National Military Medical Center, Bethesda, MD, USA
*: esingma1@jhmi.edu
纸质出版:2016-06
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Indirect traumatic optic neuropathy[J]. MMR, 2016,3(2):87-92.
Eric L. Singman, Nitin Daphalapurkar, Helen White, et al. Indirect traumatic optic neuropathy[J]. Military Medical Research, 2016, 3(2): 87-92.
Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood
and there are no confirmed protocols for prevention
mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury
such as from sports- or motor vehicle-related concussion
rather than military-related ballistic or blast damage. Research in this field will likely require the development of robust databases to identify patients with ITON and follow related outcomes
in addition to both in-vivo animal and virtual human models to study the mechanisms of damage and potential therapies.
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