A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO<sub>2</sub>

Ming Li; Ji-Hang Zhang; Guo-Xi Zhao; Shi-Zhu Bian; Xu-Bin Gao; Xi Liu; Jie Yu; Jun-Qing Dong; Guo-Zhu Chen; Hong Wang; Lan Huang

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A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂

RESEARCH | Updated：2022-12-27

- A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂
- A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂
- MMR 2015年2卷第3期页码：139-144
- Affiliations：
  
  1.Institute of Cardiovascular Diseases of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
  2.Department of Cardiology, 533 Hospital of PLA, Kunming 650000, China
  3.Department of Cadre Wards, Kunming General Hospital of Chengdu Command, Kunming 650032, China
- Author bio：
  
  Hong Wang, Email: Wanghong43@126.com
  *: Lan Huang, Email: huanglan260@126.com;
- Funds：
- DOI：
  中图分类号：
- 纸质出版：2015-09
- Accepted：
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A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂[J]. MMR, 2015,2(3):139-144.

Ming Li, Ji-Hang Zhang, Guo-Xi Zhao, et al. A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂[J]. Military Medical Research, 2015, 2(3): 139-144.
A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂[J]. MMR, 2015,2(3):139-144. DOI：

Ming Li, Ji-Hang Zhang, Guo-Xi Zhao, et al. A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂[J]. Military Medical Research, 2015, 2(3): 139-144. DOI：

摘要

Abstract

Background:

So far

there have been no measurements confirmed useful in diagnosing acute mountain sickness (AMS). The aim of this study was to determine the role of heart rate (HR) difference (ΔHR) and oxygen saturation (SaO

) as objective risk factors in aiding the diagnosis of AMS.

Methods:

A total of 1

019 participants were assigned to either the acute exposure group (AEG): from 500m to 3

700m by flight within 2.5 hours (

=752); or the pre-acclimatization group (PAG): ascended to 4

400m from 3

650m within three hours by car after adapting 33 days at 3

650m (

=267). The questionnaires or measurements of resting SaO

and HR were completed between 18 and 24 hours before departure and after arrival.

Results:

Incidence of AMS was 61.3% (461) in AEG

with 46.1% (347) mild cases and 15.2% (114) severe cases. In PAG

the incidence was 38.9% (104)

with 30.7% (82) mild cases and 8.2% (22) severe cases. The AMS subjects showed a significant increase in HR and a decrease in SaO

levels compared with the non-AMS subjects in both groups. ΔHR and post-exposure SaO

were significantly correlated with the Lake Louise Score (LLS) in both groups. Stepwise logistic regression analysis revealed the ΔHR

25 and SaO

88% in AEG as well as ΔHR

15 and SaO

86% in PAG to be independent risk factors of AMS. Combining these two measurements could specifically indicate participants with AMS

which showed a positive predictive value of 89% and specificity of 97% in AEG as well as 85% and 98% in PAG.

Conclusion:

ΔHR or SaO

as objective measurements

correlate with AMS. Combination of these two measurements may be useful as an additional specific and objective factor to further confirm the diagnosis of AMS.

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references

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A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO2

A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO2

DOI：

摘要

Abstract

关键词

Keywords

references

A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂

A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO₂