Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit

熊焕贵; 陈肇熙

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Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit

Updated：2026-03-12

- Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit
- Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit
- 解放军医学杂志（英文版） 1986年第1期页码：87-92
- Affiliations：
  
  1. Department of Physiology First Military Medical College
  2. ,Guangzhou
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1986
- Accepted：
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Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit[J]. 解放军医学杂志（英文版）, 1986,(1):87-92.

[1]熊焕贵,陈肇熙.Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit[J].Journal of Medical Colleges of PLA,1986(01):87-92.
Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit[J]. 解放军医学杂志（英文版）, 1986,(1):87-92. DOI：

[1]熊焕贵,陈肇熙.Effect of Microiontophoretically Applied GABA on Medullary Respiratory Neurons in the Region of Nucleus Tractus Solitarius of Rabbit[J].Journal of Medical Colleges of PLA,1986(01):87-92. DOI：

摘要

Abstract

<正> Experiments were performed on 19 vagotomized

curareparalyzed andartificially ventilated rabbits.3-5 barrel glass micropipettes were used torecord the extracellular discharges and to apply the ionized substances tested.Medullary respiratory units located in the region of Nucleus Treactus Soli-tarius were tested for their responsiveness to iontophoretically appliedGABA.GABA tended to inhibit not only inspiratory units but also expi-ratory ones.Of 60 units tested

49 were inhibited and the inhibitoryeffect of GABA had much to do with its quantity ejected.Phrenic nervedischarges were unchanged while the discharges of respiratory units weredepressed by GABA.The inhibitory effect of GABA could be blocked bypicrotoxin.Our results indicate that GABA may be one of the importantinhibitory neurotransmitters in the medullary“respiratory center”.

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