Mutagenicities of 22 Kinds of Foods After Nitrite Treatment
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Mutagenicities of 22 Kinds of Foods After Nitrite Treatment
Mutagenicities of 22 Kinds of Foods After Nitrite Treatment
解放军医学杂志(英文版)1986年第1期 页码:69-75
Affiliations:
1. Department of Military Hygiene Second Military Medical College
2. ,Shanghai
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DOI:
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纸质出版:1986
Accepted:
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Mutagenicities of 22 Kinds of Foods After Nitrite Treatment[J]. 解放军医学杂志(英文版), 1986,(1):69-75.
[1]印木泉.Mutagenicities of 22 Kinds of Foods After Nitrite Treatment[J].Journal of Medical Colleges of PLA,1986(01):69-75.
Mutagenicities of 22 Kinds of Foods After Nitrite Treatment[J]. 解放军医学杂志(英文版), 1986,(1):69-75.DOI:
[1]印木泉.Mutagenicities of 22 Kinds of Foods After Nitrite Treatment[J].Journal of Medical Colleges of PLA,1986(01):69-75.DOI:
Mutagenicities of 22 Kinds of Foods After Nitrite Treatment
摘要
Abstract
<正> The mutagenicities of 22 kinds of foods
including soy sauce
fish sauce
shrimp paste
sausages
sundried fishes
rice cracker
deep fried pork skin
salted vegetable and spices after nitrite treatment
were detected by meansof Ames test with preincubation.Mutagenicity assay was employed on Sal-monella typhimurium TA100
and meanwhile
the validity of each experi-ment was checked by using the known mutagen
AF-2
as the positivecontrol.16 kinds of foods showed marked direct-acting mutagenicity towardSalmonella typhimurium TA100 after nitrite treatment.Shrimp paste prod-uced in Bankok was the strongest one among these samples.Its specificmutagenicity was 37000 revertants/g.The amount of precursor
tyramine
in shrimp paste was estimated fromthe area of tyramine peak on HPLC by using the authentic tyramine as thestandard.Results showed that one gram shrimp paste contained 439μgtyramine.The mutagenicities of foods suggested that nitrosatable precursors
suchas amine or amide
were present in foods
and they could be converted intoendogenous carcinogen
nitrosamine
in vivo.Therefore
detection of muta-genicities of foods has significance in preventing cancer.
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