Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies

Zi-Xin Qiu; Frank Qian; Yan-Bo Zhang; Jun Liu; Ting-Ting Geng; Rui Li; Pang Yao; Oscar H. Franco; Eric B. Rimm; JoAnn E. Manson; An Pan; Mai-Geng Zhou; Kai Huang; Gang Liu

doi:10.1186/s40779-025-00674-4

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Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies

RESEARCH | Updated：2026-01-29

- Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies
- “In a groundbreaking study, researchers from China, the USA, and the UK have quantified the associations of risk factor control with mortality and life expectancy among individuals with type 2 diabetes (T2D). The study found that only a small proportion of participants achieved ≥ 5 combined targets, and those with a healthy lifestyle and good metabolic control had a longer life expectancy. Comprehensive management of multiple risk factors, particularly lifestyle factors, was associated with a substantial reduction in the life expectancy gap between those with and without T2D.”
- Military Medical Research Vol. 12, (2025)
- Affiliations：
  
  1.Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Laboratory of Environment and Health, and State Key Laboratory of Environment Health (Incubating),School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  2.Section of Cardiovascular Medicine, Boston Medical Center and Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA
  3.Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
  4.Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK
  5.Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  6.Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht 3584 CX, The Netherlands
  7.Department of Nutrition, Harvard T.H.Chan School of Public Health, Boston, MA 02115, USA
  8.Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA
  9.Channing Division of Network Medicine, Department of Medicine,Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
  10.Department of Medicine, Brigham and Women’s Hospital,Harvard Medical School, Harvard University, Boston, MA 02115, USA
  11.Center for Obesity and Diabetes Research, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  12.National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  13.Department of Cardiovascular Diseases, Union Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  14.Clinical Center for Human Genomic Research, Union Hospital, Huazhong University of Science and Technology, Wuhan 430030, China
  15.Department of Cardiometabolic Diseases, Remin Hospital, Wuhan University, Wuhan 430060, China
- Author bio：
  
  * Mai-Geng Zhou zhoumaigeng@ncncd.chinacdc.cn
  Kai Huang huangkai1@hust.edu.cn
  Gang Liu liugang026@hust.edu.cn
- Funds：
- DOI：10.1186/s40779-025-00674-4
  CLC：
- Received：18 June 2025，
  
  Accepted：15 November 2025，
  
  Online First：05 December 2025，
  
  Published：2025
- Accepted：
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Zi-Xin Qiu, Frank Qian, Yan-Bo Zhang, et al. Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies[J/OL]. Military Medical Research, 2025, 12.
DOI：

Zi-Xin Qiu, Frank Qian, Yan-Bo Zhang, et al. Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies[J/OL]. Military Medical Research, 2025, 12. DOI： 10.1186/s40779-025-00674-4.

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Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies

DOI：10.1186/s40779-025-00674-4