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β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition
RESEARCH | Updated：2026-01-29

    • β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition

    • “In the field of peritoneal fibrosis treatment for end-stage renal disease patients, a research team has made significant progress. They verified the role of β-catenin signaling and mesothelial cell senescence in peritoneal fibrosis, which lays a foundation for the construction of a new therapeutic intervention system.”
    • Military Medical Research   Vol. 12, (2025)

    • DOI：10.1186/s40779-025-00669-1    

      CLC：

    • Received：19 February 2025，

      Accepted：03 November 2025，

      Online First：01 December 2025，

      Published：2025

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  • Xiao-Xu Wang, Wei-Jie Zhong, Jie-Mei Li, et al. β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition[J/OL]. Military Medical Research, 2025, 12. DOI： 10.1186/s40779-025-00669-1.

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