Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases
REVIEW|Updated:2025-12-04
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Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases
“Clonal hematopoiesis of indeterminate potential (CHIP), a major risk factor for hematological malignancies, has been found to be a potent risk factor for chronic inflammation and diverse non-hematologic diseases. Expert xx explored the CHIP topic, which provides solutions to solve immune imbalance and chronic inflammation problems.”
Military Medical ResearchVol. 12, (2025)
Affiliations:
1.Department of Oncology, Affiliated Hospital of Shandong Second Medical University, Shandong Second Medical University, Weifang 261042, Shandong, China
2.Zhejiang Key Laboratory for Precision Diagnosis and Treatment of Hematological Malignancies, Hangzhou 310006, China
3.Department of Hematology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
4.Department of Biochemistry and Molecular Biology, Monash University, Clayton, Melbourne, VIC 3168, Australia
5.Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Shandong Second Medical University, Weifang 261042, Shandong, China
6.Zhejiang Provincial Clinical Research Center for Hematological Disorders, Hangzhou 310006, China
Jing-Lei Zhang, Shuo-Lan Tong, Qi-Qi Zhuang, et al. Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases[J/OL]. Military Medical Research, 2025, 12.
DOI:
Jing-Lei Zhang, Shuo-Lan Tong, Qi-Qi Zhuang, et al. Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases[J/OL]. Military Medical Research, 2025, 12. DOI: 10.1186/s40779-025-00654-8.
Clonal hematopoiesis of indeterminate potential: a multisystem hub bridging hematopoietic dysfunction with non-hematopoietic diseases