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Substantia nigra related gene polymorphisms associated with antipsychotic-induced acute movement disorders: a genome-wide association study and multi-ancestry validation in schizophrenia
RESEARCH | Updated:2026-03-26
    • Substantia nigra related gene polymorphisms associated with antipsychotic-induced acute movement disorders: a genome-wide association study and multi-ancestry validation in schizophrenia

    • A new study introduces research progress in the field of antipsychotic-induced movement disorders (AIMDs). Experts conducted a genome-wide association study (GWAS) across multiple cohorts, identifying key genetic loci associated with AIMDs. The findings highlight the role of substantia nigra related gene polymorphisms in AIMDs, opening a new direction for personalized treatment approaches in schizophrenia.
    • Military Medical Research   Vol. 13, Issue 2, Pages: 185-197(2026)
    • DOI:10.1186/s40779-025-00636-w    

      CLC:
    • Received:02 April 2025

      Accepted:25 July 2025

      Online First:19 August 2025

      Published:2026-02

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  • Zhe Lu, Yao-Yao Sun, Zhe-Wei Kang, et al. Substantia nigra related gene polymorphisms associated with antipsychotic-induced acute movement disorders: a genome-wide association study and multi-ancestry validation in schizophrenia[J]. Military Medical Research, 2026, 13(2): 185-197. DOI: 10.1186/s40779-025-00636-w.

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