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Salmonella enterica mediated epigenetic promotion of fibrosis is a novel factor in benign prostatic hyperplasia
RESEARCH | Updated:2025-12-13
    • Salmonella enterica mediated epigenetic promotion of fibrosis is a novel factor in benign prostatic hyperplasia

    • Reporting on the latest research in the field of benign prostatic hyperplasia (BPH), experts have established a novel link between microbial presence and prostatic fibrosis. The study, which provides solutions to address the ineffectiveness of current BPH treatments, verified that Salmonella enterica promotes prostatic fibrosis through ALKBH5-m6A-GPX4-mediated ferroptosis, laying a foundation for the construction of new therapeutic targets and personalized strategies.
    • Military Medical Research   Vol. 12, Issue 9, Pages: 1350-1368(2025)
    • DOI:10.1186/s40779-025-00614-2    

      CLC:
    • Received:30 December 2024

      Accepted:29 April 2025

      Online First:29 May 2025

      Published:2025-09

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  • Cong Zhu, Lu-Yao Li, Ming-Hui Shi, et al. Salmonella enterica mediated epigenetic promotion of fibrosis is a novel factor in benign prostatic hyperplasia[J]. Military Medical Research, 2025, 12(9): 1350-1368. DOI: 10.1186/s40779-025-00614-2.

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