Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder

Murray J. Andrews; David H. Salat; William P. Milberg; Regina E. McGlinchey; Catherine B. Fortier

doi:10.1186/s40779-024-00557-0

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Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder

RESEARCH | Updated：2025-12-13

- Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder
- “In a recent study, researchers at VA Boston, MA, investigated the relationship between sleep quality and brain volume changes in veterans, particularly those with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). The study found that poor sleep quality is significantly associated with decreased cortical thickness in veterans with mTBI, either alone or comorbid with PTSD, primarily within frontal regions. This finding may have important implications for the treatment of veterans who have sustained mTBI.”
- Military Medical Research Vol. 12, Issue 5, Pages: 716-726(2025)
- Affiliations：
  
  1.Boston University Chobanian and Avedisian School of Medicine, Boston, MA 02118, USA
  2.Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA 02130, USA
  3.Department of Psychiatry, Harvard Medical School, Boston, MA 02138, USA
  4.Department f Psychiatry, Boston University School of Medicine, Boston, MA 02130, USA
  5.Neuroimaging Research for Veterans Center, VA Boston Healthcare System, Boston, MA 02130, USA
  6.Anthinoula A. Martinos Center for Biomedical Imaging, Boston, MA 02129, USA
  7.Geriatric Research, Educational and Clinical Center (GRECC), VA Boston Healthcare System, Boston, MA 02130, USA
- Author bio：
  
  * catherine_fortier@hms.harvard.edu
- Funds：
- DOI：10.1186/s40779-024-00557-0
  CLC：
- Published：2025-05
- Accepted：
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Cite this article as: Andrews MJ, Salat DH, Milberg WP, McGlinchey RE, Fortier CB. Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder. Mil Med Res. 2024;11(1):51.
DOI：

Cite this article as: Andrews MJ, Salat DH, Milberg WP, McGlinchey RE, Fortier CB. Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder. Mil Med Res. 2024;11(1):51. DOI： 10.1186/s40779-024-00557-0.

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Poor sleep and decreased cortical thickness in veterans with mild traumatic brain injury and post-traumatic stress disorder

DOI：10.1186/s40779-024-00557-0