Advances in the mechanism of small nucleolar RNA and its role in DNA damage response

Li-Ping Shen; Wen-Cheng Zhang; Jia-Rong Deng; Zhen-Hua Qi; Zhong-Wu Lin; Zhi-Dong Wang

doi:10.1186/s40779-024-00553-4

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Advances in the mechanism of small nucleolar RNA and its role in DNA damage response

REVIEW | Updated：2025-12-13

- Advances in the mechanism of small nucleolar RNA and its role in DNA damage response
- “In the field of genomic stability maintenance, experts have systematically reviewed the research progress of small nucleolar RNAs (snoRNAs) in DNA damage response (DDR). This study explores the biosynthesis, classification, and regulatory mechanisms of snoRNAs, as well as their role in DDR and significance in disease diagnosis and treatment, laying a foundation for the construction of the snoRNA system.”
- Military Medical Research Vol. 12, Issue 6, Pages: 903-937(2025)
- Affiliations：
  
  1.Department of Radiobiology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing 100850, China
  2.Graduate Collaborative Training Base of Academy of Military Sciences, Hengyang Medical School, University of South China, Hengyang 421001, Hunan, China
- Author bio：
  
  * wangzhidong@bmi.ac.cn; wangzhidong1977@126.com
- Funds：
- DOI：10.1186/s40779-024-00553-4
  CLC：
- Published：2025-06
- Accepted：
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Cite this article as: Shen LP, Zhang WC, Deng JR, Qi ZH, Lin ZW, Wang ZD. Advances in the mechanism of small nucleolar RNA and its role in DNA damage response. Mil Med Res. 2024;11(1):53.
DOI：

Cite this article as: Shen LP, Zhang WC, Deng JR, Qi ZH, Lin ZW, Wang ZD. Advances in the mechanism of small nucleolar RNA and its role in DNA damage response. Mil Med Res. 2024;11(1):53. DOI： 10.1186/s40779-024-00553-4.

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Advances in the mechanism of small nucleolar RNA and its role in DNA damage response

DOI：10.1186/s40779-024-00553-4