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TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients
RESEARCH | Updated：2025-12-13

    • TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients

    • “In the field of Parkinson's disease treatment, researchers have made significant progress. They found that transforming growth factor-β1 (TGF-β1) secreted from hypoxia-preconditioned olfactory mucosa-mesenchymal stem cells (hOM-MSCs) plays a critical role in modulating mitochondrial function recovery in dopaminergic neurons, providing a new direction for PD research.”
    • Military Medical Research   Vol. 12, Issue 5, Pages: 686-715(2025)

    • DOI：10.1186/s40779-024-00550-7    

      CLC：

    • Published：2025-05

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  • Cite this article as: Zhuo Y, Li WS, Lu W, Li X, Ge LT, Huang Y, et al. TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson’s disease models and patients. Mil Med Res. 2024;11(1):48. DOI： 10.1186/s40779-024-00550-7.

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