Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family
REVIEW|Updated:2025-12-13
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Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family
“Reporting on the latest research, the paper delves into the role of fibroblast growth factor (FGF) signaling in orthopedic diseases, highlighting its regulation of cartilage and bone health. Expert research has identified potential FGF signaling targets, paving the way for future therapeutic strategies to combat conditions like osteoarthritis and osteoporosis.”
Military Medical ResearchVol. 12, Issue 5, Pages: 764-787(2025)
Affiliations:
1.Department of Orthopedics, Xiangya Hospital, Central South University, Changsha 410008, China
2.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China
3.Department of Plastic and Cosmetic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
4.Xiangya School of Medicine Central, South University, Changsha 410083, China
6.Faculty of Medicine, Research Unit of Health Sciences and Technology, University of Oulu, Oulu 90014, Finland
7.Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, 08406 Vilnius, Lithuania
8.Department of Rheumatology and Clinical Immunology, Universitair Medisch Centrum Utrecht, Utrecht 3508, GA, the Netherlands
9.Department of Joint Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
10.World Health Organization Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Université de Liège, B-4000 Liège, Belgium
Cite this article as: Li HZ, Zhang Jl, Yuan DL, Xie WQ, Ladel CH, Mobasheri A, et al. Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family. Mil Med Res. 2024;11(1):40.
DOI:
Cite this article as: Li HZ, Zhang Jl, Yuan DL, Xie WQ, Ladel CH, Mobasheri A, et al. Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family. Mil Med Res. 2024;11(1):40. DOI: 10.1186/s40779-024-00544-5.
Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family
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