Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction
REVIEW|Updated:2025-12-13
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Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction
“In the field of sepsis research, this paper highlights the emerging significance of exosomes in modulating immune responses, metabolic reprogramming, coagulopathy, and organ dysfunction. Expert xx established the xx system, which provides solutions to solve the complex pathophysiology of sepsis and lays a foundation for the construction of novel interventions to mitigate severe outcomes.”
Military Medical ResearchVol. 12, Issue 2, Pages: 264-284(2025)
Affiliations:
1.Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
2.Department of Anesthesiology, Shenzhen Hospital, Southern Medical University, Shenzhen 518110, Guangzhou, China
3.Research and Development, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
4.Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
5.McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA
Cite this article as: Gong T, Liu YT, Fan J. Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction. Mil Med Res. 2024;11(1):24.
DOI:
Cite this article as: Gong T, Liu YT, Fan J. Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction. Mil Med Res. 2024;11(1):24. DOI: 10.1186/s40779-024-00527-6.
Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction