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ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression
RESEARCH | Updated：2025-12-13

    • ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression

    • “In the field of prostate cancer treatment, researchers have identified ADP-dependent glucokinase (ADPGK) as a crucial target. The study found that high ADPGK expression is associated with poor survival outcomes in prostate cancer patients. ADPGK accelerates cancer glycolysis and progression by activating the ALDOC-AMPK signaling pathway, laying a foundation for the construction of a new treatment and prognosis evaluation system for prostate cancer.”
    • Military Medical Research   Vol. 11, Issue 5, Pages: 643-662(2024)

    • DOI：10.1186/s40779-023-00500-9    

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    • Published：2024-10

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  • Cite this article as: Xu H, Li YF, Yi XYL, Zheng XN, Yang Y, Wang Y, et al. ADP-dependent glucokinase controls metabolic fitness in prostate cancer progression. Mil Med Res. 2023;10(1):64. DOI： 10.1186/s40779-023-00500-9.

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