Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

Ze-Qin Wen; Jun Lin; Wen-Qing Xie; Yun-Han Shan; Ge-Hua Zhen; Yu-Sheng Li

doi:10.1186/s40779-023-00485-5

Your Location：

Home >

Browse articles >

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

REVIEW | Updated：2025-12-13

- Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases
- “Reporting on the latest research, experts have integrated up-to-date findings on endoplasmic reticulum stress in the pathogenesis of degenerative musculoskeletal diseases, laying a foundation for the construction of ER stress modulators in clinical trials.”
- Military Medical Research Vol. 11, Issue 6, Pages: 839-862(2024)
- Affiliations：
  
  1.Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha 410008, China
  2.Xiangya School of Medicine, Central South University, Changsha 410013, China
  3.Department of Orthopaedics, Suzhou Dushu Lake Hospital, Dushu Lake Hospital Affiliated to Soochow University, Medical Center of Soochow University, Suzhou 215001, China
  4.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China
  5.Department of General Surgery, Xiangya Hospital, Central South University, Changsha 410008, China
  6.Department of Orthopaedic Surgery, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA
- Author bio：
  
  *gzhen1@jhmi.edu;
  liyusheng@csu.edu.cn
- Funds：
- DOI：10.1186/s40779-023-00485-5
  CLC：
- Published：2024-12
- Accepted：
Scan QR Code
Cite this article as: Wen ZQ, Lin J, Xie WQ, Shan YH, Zhen GH, Li YS. Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases. Mil Med Res. 2023;10(1):54.
DOI：

Cite this article as: Wen ZQ, Lin J, Xie WQ, Shan YH, Zhen GH, Li YS. Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases. Mil Med Res. 2023;10(1):54. DOI： 10.1186/s40779-023-00485-5.

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

The emerging role of ferroptosis in the pathological development and progression of sepsis

China stroke surveillance report 2021

Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)

Military traumatic brain injury: a challenge straddling neurology and psychiatry

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia (2021 Edition)

Related Author

Hui-Ting Zhou

Jie Huang

Ya-Kun Liu

Jiang-Huai Wang

Jian Wang

Wen-Jun Tu

Long-De Wang

on behalf of the Special Writing Group of China Stroke Surveillance Report

Related Institution

Institute of Pediatric Research, Children’s Hospital of Soochow University

Department of Surgery, Children’s Hospital of Soochow University

Department of Academic Surgery, University College Cork, Cork University Hospital

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University

School of Public Health, Peking University

⁰

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

DOI：10.1186/s40779-023-00485-5