Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications

Shuai Liu; Jiang-Ming Yu; Yan-Chang Gan; Xiao-Zhong Qiu; Zhe-Chen Gao; Huan Wang; Shi-Xuan Chen; Yuan Xiong; Guo-Hui Liu; Si-En Lin; Alec McCarthy; Johnson V. John; Dai-Xu Wei; Hong-Hao Hou

doi:10.1186/s40779-023-00448-w

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Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications

REVIEW | Updated：2025-12-13

- Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications
- “Biomimetic materials, as a new alternative in tissue engineering and regenerative medicine, have made significant progress. This paper summarizes recent advances in the preparation, functionality, and applications of biomimetic natural biomaterials, laying a foundation for the construction of living implants.”
- Military Medical Research Vol. 11, Issue 1, Pages: 50-79(2024)
- Affiliations：
  
  1.Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, the Fifth Affiliated Hospital, School of Basic Medical Science, Southern Medical University, Guangzhou 510900, China
  2.Department of Orthopedics, Tongren Hospital, Shanghai Jiao Tong University, Shanghai 200336, China
  3.The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen 518033, Guangdong, China
  4.Engineering Research Center of Clinical Functional Materials and Diagnosis & Treatment Devices of Zhejiang Province, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325011, Zhejiang, China
  5.Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  6.Department of Orthopaedics and Traumatology, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR 999077, China
  7.Department of Functional Materials, Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90064, USA
  8.Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68130, USA
  9.Zigong Affiliated Hospital of Southwest Medical University, Zigong Psychiatric Research Center, Zigong Institute of Brain Science, Zigong 643002, Sichuan, China
  10.Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Department of Life Sciences and Medicine, Northwest University, Xi’an 710127, China
- Author bio：
  
  * wangh679@mail.sysu.edu.cn;
  chensx@ucas.ac.cn;
  daviddxwei@163.com;
  ss.hhh89@hotmail.com
- Funds：
- DOI：10.1186/s40779-023-00448-w
  CLC：
- Published：2024-02
- Accepted：
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Cite this article as: Liu S, Yu JM, Gan YC, Qiu XZ, Gao ZC, Wang H, et al. Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications. Mil Med Res. 2023;10(1):16.
DOI：

Cite this article as: Liu S, Yu JM, Gan YC, Qiu XZ, Gao ZC, Wang H, et al. Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications. Mil Med Res. 2023;10(1):16. DOI： 10.1186/s40779-023-00448-w.

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Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications

DOI：10.1186/s40779-023-00448-w