Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)

Ying-Hui Jin; Xian-Tao Zeng; Tong-Zu Liu; Zhi-Ming Bai; Zhong-Ling Dou; De-Gang Ding; Zhi-Lu Fan; Ping Han; Yi-Ran Huang; Xing Huang; Ming Li; Xiao-Dong Li; Yi-Ning Li; Xu-Hui Li; Chao-Zhao Liang; Jiu-Min Liu; Hong-Shun Ma; Juan Qi; Jia-Qi Shi; Jian Wang; De-Lin Wang; Zhi-Ping Wang; Yun-Yun Wang; Yong-Bo Wang; Qiang Wei; Hai-Bo Xia; Jin-Chun Xing; Si-Yu Yan; Xue-Pei Zhang; Guo-You Zheng; Nian-Zeng Xing; Da-Lin He; Xing-Huan Wang

doi:10.1186/s40779-022-00406-y

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Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)

POSITION ARTICLE AND GUIDELINE | Updated：2023-05-10

- Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)
- Military Medical Research Vol. 10, Issue 2, Pages: 141-161(2023)
- Affiliations：
  
  1.Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
  2.Department of Urology, Institute of Urology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
  3.Department of Urology, Haikou People's Hospital, Haikou Affiliated Hospital of Central South University Xiangya School of Medicine, Haikou 570208, China
  4.Department of Urology, the First Affiliated Hospital and College of Clinical Medicine, Henan University of Science and Technology, Luoyang 450052, Henan, China
  5.Department of Urology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou 450003, China
  6.Department of Urology, the Second Hospital of Dalian Medical University, Dalian 116023, Liaoning, China
  7.Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China
  8.Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200120, China
  9.Department of Urology, the People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830002, China
  10.Department of Urology, Huaihe Hospital of Henan University, Kaifeng 475000, Henan, China
  11.Institutes of Evidence-Based Medicine and Knowledge Translation, Henan University, Kaifeng 475000, Henan, China
  12.Department of Urology, the Second Affiliated Hospital and Second Clinical Medical College of Fujian Medical University, Quanzhou 362000, Fujian, China
  13.Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China
  14.Department of Urology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
  15.Department of Urology, Tianjin First Central Hospital, Tianjin 300190, China
  16.Department of Urology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  17.Department of Urology, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China
  18.Department of Urology, Qinghai University Affiliated Hospital, Xining 810012, China
  19.Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China
  20.Department of Urology, Institute of Urology, Lanzhou University Second Hospital, Key Laboratory of Urological Diseases in Gansu Province, Lanzhou 730030, China
  21.Department of Urology, Chifeng Cancer Hospital, the Second Affiliated Hospital of Chifeng University, Chifeng 024000, Inner Mongolia Autonomous Region, China
  22.Key Laboratory of Urinary Tract Tumors and Calculi, Department of Urology, the First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian, China
  23.Department of Urology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
  24.Department of Urology, the Second Division of the First Hospital of Jilin University, Changchun 130061, China
  25.Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  26.Department of Urology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
- Author bio：
  
  * xingnianzeng@126.com;
  hedl@xjtu.edu.cn;
  wangxinghuan1965@163.com
- Funds：
- DOI：10.1186/s40779-022-00406-y
  CLC：
- Published：2023-04
- Accepted：
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Cite this article as: Jin YH, Zeng XT, Liu TZ, Bai ZM, Dou ZL, Ding DG, et al. Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition). Mil Med Res. 2022;9(1):44.
DOI：

Cite this article as: Jin YH, Zeng XT, Liu TZ, Bai ZM, Dou ZL, Ding DG, et al. Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition). Mil Med Res. 2022;9(1):44. DOI： 10.1186/s40779-022-00406-y.

摘要

Abstract

Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high incidence worldwide

resulting in a great disease burden. Treatment and surveillance are the most important part of NIMBC management. In 2018

we issued "Treatment and surveillance for non-muscle-invasive bladder cancer in China: an evidence-based clinical practice guideline" . Since then

various studies on the treatment and surveillance of NMIBC have been published. There is a need to incorporate these materials and also to take into account the relatively limited medical resources in primary medical institutions in China. Developing a version of guideline which takes these two issues into account to promote the management of NMIBC is therefore indicated. We formed a working group of clinical experts and methodologists. Through questionnaire investigation of clinicians including primary medical institutions

24 clinically concerned issues

involving transurethral resection of bladder tumor (TURBT)

intravesical chemotherapy and intravesical immunotherapy of NMIBC

and follow-up and surveillance of the NMIBC patients

were determined for this guideline. Researches and recommendations on the management of NMIBC in databases

guideline development professional societies and monographs were referred to

and the European Association of Urology was used to assess the certainty of generated recommendations. Finally

we issued 29 statements

among which 22 were strong recommendations

and 7 were weak recommendations. These recommendations cover the topics of TURBT

postoperative chemotherapy after TURBT

Bacillus Calmette–Guérin (BCG) immunotherapy after TURBT

combination treatment of BCG and chemotherapy after TURBT

treatment of carcinoma

in situ

radical cystectomy

treatment of NMIBC recurrence

and follow-up and surveillance. We hope these recommendations can help promote the treatment and surveillance of NMIBC in China

especially for the primary medical institutions.

关键词

Keywords

references

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