Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma

Li-Bo Zhang; Rong-Rong Pang; Qing-Hua Qiao; Zhi-Hua Wang; Xin-Yi Xia; Chang-Jun Wang; Xiao-Li Xu

doi:10.1186/s40779-020-00273-5

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Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma

CASE REPORT | Updated：2023-02-28

- Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma
- Military Medical Research Vol. 8, Issue 1, Pages: 132-137(2021)
- Affiliations：
  
  1.COVID-19 Research Center, Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, the First School of Clinical Medicine, Southern Medical University, Nanjing 210002, Jiangsu, China
  2.Department of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing 210003, Jiangsu, China
  3.Medical and Technical Support Department, Pingdingshan Medical District, the 989th Hospital, Pingdingshan 467000, Henan, China
  4.Department of Laboratory Medicine & Blood Transfusion, Wuhan Huoshenshan Hospital, Wuhan 430100, Hubei, China
  5.Department of Laboratory Medicine & Blood Transfusion, the 907th Hospital, Nanping 350702, Fujian, China
  6.Joint Expert Group for COVID-19, Wuhan Huoshenshan Hospital, Wuhan 430100, Hubei, China
  7.Center for Disease Control and Prevention of PLA, No. 20 Dongda Street, Fengtai District, Beijing 100071, China
  8.Department of Medical Administration, Jinling Hospital, Nanjing University School of Medicine, No. 305 East Zhongshan Road, Nanjing 210002, Jiangsu, China
- Author bio：
  
  * xinyixia@nju.edu.cn;
  science2008@hotmail.com;
  xxl2019kt@sina.com
- Funds：
- DOI：10.1186/s40779-020-00273-5
  CLC：
- Published：2021-03
- Accepted：
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Zhang et al.: Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma. Mil Med Res, 2020, 7: 45.
DOI：

Zhang et al.: Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma. Mil Med Res, 2020, 7: 45. DOI： 10.1186/s40779-020-00273-5.

摘要

Abstract

Background:

Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients

but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients.

Case presentation:

We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration.

Conclusion:

When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment

alternative therapy with convalescent plasma administration may be considered.

关键词

Keywords

references

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