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Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines
- Military Medical Research Vol. 7, Issue 2, Pages: 209-227(2020)
- Affiliations：
1.Department of Otolaryngology-Head and Neck Surgery, National University Hospital System, Singapore, Singapore
2.Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
- Author bio：
* entoyk@nus.edu.sg;
entwdy@nus.edu.sg
- Funds：
DOI：10.1186/s40779-020-00251-x
CLC：-
Published：2020-06
- Accepted：
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Cite this article as: Xu et al.: Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines. Mil Med Res, 2020, 7: 22
Cite this article as: Xu et al.: Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines. Mil Med Res, 2020, 7: 22 DOI： 10.1186/s40779-020-00251-x.
摘要
Abstract
The coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected persons
many of whom require intensive care support or eventually succumb to the illness. The outbreak is managed by a combination of disease containment
via
public health measures and supportive care for those who are affected. To date
there is no specific anti-COVID-19 treatment. However
the urgency to identify treatments that could turn the tide has led to the emergence of several investigational drugs as potential candidates to improve outcome
especially in the severe to critically ill. While many of these adjunctive drugs are being investigated in clinical trials
professional bodies have attempted to clarify the setting where the use of these drugs may be considered as off-label or compassionate use. This review summarizes the clinical evidence of investigational adjunctive treatments used in COVID-19 patients as well as the recommendations of their use from guidelines issued by international and national organizations in healthcare.
关键词
Keywords
references
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