Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China

Wei-Wei Chen; Wen Xu; Yang-Xin Xie; Yun-Hui Zhang; Dan Wu; Fu-Sheng Wang; Min Zhao

doi:10.1186/s40779-017-0120-y

Your Location：

Home >

Browse articles >

Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China

RESEARCH | Updated：2026-03-12

- Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China
- Military Medical Research Vol. 4, Issue 4, Pages: 193-199(2017)
- Affiliations：
  
  1.Treatment and Research Center for Infectious Diseases, 302 Hospital of PLA, Beijing 100039, China
  2.Center for Medical information, 302 Hospital of PLA, Beijing 100039, China
- Author bio：
  
  *: fswang302@163.com;
  drzhaomin@sina.com
- Funds：
- DOI：10.1186/s40779-017-0120-y
  CLC：
- Published：2017-12
- Accepted：
Scan QR Code
Chen et al.: Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China. Mil Med Res, 2017, 4: 10
DOI：

Chen et al.: Surveillance for respiratory infectious diseases caused by 6 common viruses in a recruit training site in the Northern region of China. Mil Med Res, 2017, 4: 10 DOI： 10.1186/s40779-017-0120-y.

摘要

Abstract

Background:

Recruit training sites are places with a high incidence of respiratory infectious diseases. Effective surveillance for acute respiratory infectious diseases in a recruit training site is an important way to prevent disease outbreaks.

Methods:

Eight hundred recruits (722 males and 78 females) enlisted in autumn 2015 received a background survey within 24h of settlement at the recruit training site

including their general personal information

vaccination history

mental status and clinical symptoms. Then

nasopharyngeal swabs of these recruits were collected to detect common respiratory pathogens [influenza virus type A

influenza virus type B

adenovirus (Adv)

human respiratory syncytial virus

human bocavirus and human metapneumovirus] by PCR. In addition

fasting venous blood was collected in the morning for Adv IgG antibody detection. During the three months of training

the recruits were monitored for symptoms of respiratory infection

and nasopharyngeal swabs were collected from those with an axillary temperature ≥38

℃

and other respiratory symptoms within 4h of symptom onset. Samples were further examined by PCR.

Results:

Among the 795 effective nasopharyngeal swab samples collected during survey

two cases of group C type 1 Adv were identified by PCR. During the 3 months of training

fever and respiratory symptoms occurred in 39 recruits (incidence rate of 4.9%) and 5 cases of Adv were detected (positive rate of 12.8%). Genotyping showed 3 cases of type 4 Adv and 2 of type 3 Adv. No type 7

14 or 55 Adv was detected. The Adv-IgG positive rate of recruits was 48.2%. Among the 5 Adv positive cases with fever and respiratory symptoms

4 were Adv-IgG positive.

Conclusion:

The pathogen carrier rate in recruits was low

and only group C Adv

which causes mild infection in humans

was detected. No respiratory outbreak was observed at the recruit training site

and sporadic cases were mainly caused by type 3 and type 4 Adv.

关键词

Keywords

references

Murray CK , Horvath LL . An approach to prevention of infectious diseases during military deployments . Clin Infect Dis . 2007 ; 44 ( 3 ): 424 - 30 .

Van Kerkhove MD , Cooper MJ , Cost AA , Sanchez JL , Riley S . Risk factors for severe outcomes among members of the United States military hospitalized with pneumonia and influenza, 2000–2012 . Vaccine . 2015 ; 33 ( 49 ): 6970 - 6 .

Pang J , Jin J , Loh JP , Tan BH , Koh WH , Ng SH , et al . Risk factors for febrile respiratory illness and mono-viral infections in a semi-closed military environment: a case-control study . BMC Infect Dis . 2015 ; 15 : 288 .

Xie YX , Tu B , Chen WW , Zhou ZP , Nie WM , Wang CL , et al . Clinical characteristics of 80 hospitalized cases of human adenovirus type 55 infection . Infect Dis Info . 2013 ; 26 ( 1 ): 45 - 7 .

Tu B , Xie YX , Zhang X , Chen WW , Zhou ZP , Qin EQ , et al . Chest CT characteristics of 121 adult patients with adenovirus type 55 pneumonia . Infect Dis Info . 2014 ; 1 : 49 - 51 .

Chen WW , Nie WM , Xu W , Xie YX , Tu B , Zhao P , et al . Cross-sectional study of the relationship of peripheral blood cell profiles with severity of infection by adenovirus type 55 . BMC Infect Dis . 2014 ; 14 : 147 .

Zhang NC , Li WG , Tu B , Xie YX , Chen WW , Zhao M . Clinical characteristics analysis of adult human adenovirus type 7 infection . Chin J Infect Dis . 2014 ; 32 ( 4 ): 25 - 8 .

Zhao S , Wan C , Ke C , Seto J , Dehghan S , Zou L , et al . Re-emergent human adenovirus genome type 7 caused an acute respiratory disease outbreak in Southern China after a twenty-one year absence . Sci Rep . 2014 ; 4 : 7365 .

Li T , Zhang JL , Li PC . Practices and discussion on establishing respiratory infectious pathogen monitoring sites in the elementary troops . People’s Mil Surg . 2015 ; 6 : 635 - 6 .

Sanchez JL , Cooper MJ , Myers CA , Cummings JF , Vest KG , Russell KL , et al . Respiratory infections in the U.S. military: recent experience and control . Clin Microbiol Rev . 2015 ; 28 ( 3 ): 743 - 800 .

Shanks GD . How World War 1 changed global attitudes to war and infectious diseases . Lancet . 2014 ; 384 ( 9955 ): 1699 - 707 .

Guo PY , Chen HW , You LH , Tong CT , Li XF , Huo XR . Analysis of the rapid detection for pathogens in recruits with upper respiratory tract infection in a PLA unit near Beijing . Med Pharm J Chin PLA . 2013 ; 11 : 91 - 3 .

Geng ZK . Epidemiological characteristics analysis of respiratory infectious diseases . Med People . 2014 ; 27 ( 5 ): 270 .

Lan XX , Yin BL , ZhaLa G , Zhang MS , Wang SX , Zhao HB . Analysis on the characteristics of respiratory diseases in recruits during mass training . Med J Chin PLA . 2010 ; 35 ( 1 ): 107 - 9 . Article in China .

Kajon AE , Dickson LM , Metzgar D , Houng HS , Lee V , Tan BH . Outbreak of febrile respiratory illness associated with adenovirus 11a infection in a Singapore military training cAMP . J Clin Microbiol . 2010 ; 48 ( 4 ): 1438 - 41 .

Professional Committee of Infectious Diseases of PLA . Guidelines on adenovirus infections diagnosis and treatment . Med J Chin PLA . 2013 ; 38 ( 7 ): 529 - 34 . Article in China .

Potter RN , Cantrell JA , Mallak CT , Gaydos JC . Adenovirus-associated deaths in US military during post vaccination period, 1999–2010 . Emerg Infect Dis . 2012 ; 18 ( 3 ): 507 - 9 .

Zhu WW , Wu WW , Yang JC , Du YG , Tang LY , Tong J . Epidemic investigation for adenovirus infection among normal population in XuZhou region . Chin J Sch Doct . 2016 ; 5 : 359 - 60 .

Sheng HY . Investigation for adenovirus neutralizing antibodies in the serum of the general population, and identification and analysis for neutralizing epitope of adenovirus 3 type . Guangdong : South Med Univ ; 2013 .

Li SL , Deng B , Yang HS . Analysis of outbreaks of type 55 adenovirus epidemics and the strategy on prevention and control . J Prev Med Chin PLA . 2015 ; 2 : 214 .

Radin JM , Hawksworth AW , Blair PJ , Faix DJ , Raman R , Russell KL , et al . Dramatic decline of respiratory illness among US military recruits after the renewed use of adenovirus vaccines . Clin Infect Dis . 2014 ; 59 ( 7 ): 962 - 8 .

Qiu S , Li P , Liu H , Wang Y , Liu N , Li C , et al . Whole-genome sequencing for tracing the transmission link between two ARDs outbreaks caused by a novel HAdV serotype 7 variant, China . Sci Rep . 2015 ; 5 : 13617 .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology

Molecular diagnostic approaches for enteric parasites: an issue of relevance for deployed soldiers?

Treatment and surveillance for non-muscle-invasive bladder cancer: a clinical practice guideline (2021 edition)

Data mining in clinical big data: the frequently used databases, steps, and methodological models

Related Author

Jun Lyu

An-Ding Xu

Xiang-Yu Wang

Zheng Chen

Yu-Jiao Wang

Chi-Kwan Tsang

Yuan-Jie Li

Wen-Qiang Che

Related Institution

Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization

Department of Neurology, the First Affiliated Hospital of Jinan University

Department of Urology, the First Affiliated Hospital of Jinan University

Department of Pathology, Shanxi Provincial People’s Hospital

Clinical Neuroscience Institute, the First Affiliated Hospital of Jinan University

⁰