Olfaction as a soldier - a review of the physiology and its present and future use in the military

Palaniappan Ganesh Nagappan; Somasundram Subramaniam; De-Yun Wang

doi:10.1186/s40779-017-0119-4

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Olfaction as a soldier - a review of the physiology and its present and future use in the military

REVIEW | Updated：2026-03-12

- Olfaction as a soldier - a review of the physiology and its present and future use in the military
- Military Medical Research Vol. 4, Issue 3, Pages: 157-169(2017)
- Affiliations：
  
  1.School of Clinical Medicine, University of Cambridge, Cambridge, UK
  2.Department of Otolaryngology, Ng Teng Fong General Hospital, Singapore, Singapore
  3.Department of Otolaryngology, National University of Singapore, National University Health System, Singapore, Singapore
  4.Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, Singapore 119228, Singapore
- Author bio：
  
  *: entwdy@nus.edu.sg
- Funds：
- DOI：10.1186/s40779-017-0119-4
  CLC：
- Published：2017-09
- Accepted：
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Nagappan et al.: Olfaction as a soldier– a review of the physiology and its present and future use in the military. Mil Med Res, 2017, 4: 9
DOI：

Nagappan et al.: Olfaction as a soldier– a review of the physiology and its present and future use in the military. Mil Med Res, 2017, 4: 9 DOI： 10.1186/s40779-017-0119-4.

摘要

Abstract

Olfaction is one of our 5 main qualitative sensory abilities. In this review

we have examined the physiology of olfaction from the olfactory receptor to the brain. Through analyzing the physiology of olfaction

we have found that the biochemistry of olfactory nerve stimulation is unique from that of other similar pathways. Upon receiving large amounts of input from the olfactory nerve

the olfactory bulb

followed by several layers of centrifugal and centripetal processing in the brain

has to sort the information from the input as well as integrate it with other inputs from the brain to develop a coherent understanding of the input. We then examined the implications of olfaction in the military

the practical applications of electronic noses and problems associated with injury to olfaction that could affect compensation and combat worthiness of a soldier following injury. In the military

olfaction can allow the army to perform at its best through 4 main methods

namely ensuring olfaction is consistent with other dimensions of perception (ensuring optimal olfaction ability in all soldiers in combat)

understanding the impact of different common combat environments on the sense of smell

utilizing odor as a defense mechanism and using olfactory aids when necessary. Electronic noses are olfactory aids that have a large potential in the military ranging from saving lives through the detection of explosives to potential methods for improving combustion efficiency. There are several problems associated with injury to olfaction that should be considered when deciding on compensation and combat worthiness of the soldier following an injury.

关键词

Keywords

references

Pinel JP . Biopsychology . London : Pearson Education ; 2009 .

Elmar Schmeisser KAP , Letowski T . Olfaction Warfare: Odor as Sword and Shield ; 2013 . p. 52 .

Behl C , Holsboer F . Oxidative stress in the pathogenesis of Alzheimer’s disease and antioxidant neuroprotection . Fortschr Neurol Psychiatr . 1998 ; 66 : 113 - 21 .

Ryan MA , Homer ML , Buehler MG , Manatt KS , Lau B , Karmon D , et al . Monitoring space shuttle Air for selected contaminants using an electronic nose . Handb Machine Olfaction: Electron Nose Technol Weinheim: Hoboken: Wiley VCH . 1998 ; 1 : 525 - 46 .

Margot C . A noseful of objects . Nat Neurosci . 2009 ; 12 : 813 - 4 .

Vermetten E , Bremner JD . Olfaction as a traumatic reminder in posttraumatic stress disorder: case reports and review . J Clin Psychiatry . 2003 ; 64 : 202 - 7 .

Shipley M , Reyes P . Anatomy of the human olfactory bulb and central olfactory pathways . In: Laing DG , Doty RL , Breipohl W , editors . The human sense of smell . Berlin, Heidelberg : Springer Berlin Heidelberg ; 1991 . p. 29 - 60 .

de March CA , Ryu S , Sicard G , Moon C , Golebiowski J . Structure-odour relationships reviewed in the postgenomic era . Flavour Fragr J . 2015 ; 30 : 342 - 61 .

Leinders-Zufall T , Shepherd GM , Zufall F . Regulation of cyclic nucleotidegated channels and membrane excitability in olfactory receptor cells by carbon monoxide . J Neurophysiol . 1995 ; 74 : 1498 - 508 .

Kawai F , Kurahashi T , Kaneko A . Adrenaline enhances odorant contrast by modulating signal encoding in olfactory receptor cells . Nat Neurosci . 1999 ; 2 : 133 - 8 .

Kawai F . Simulation analysis of effects of adrenaline on spike generation in olfactory receptor cells . Chem Senses . 1999 ; 24 : 701 - 4 .

Hamilton KA , Heinbockel T , Ennis M , Szabo G , Erdelyi F , Hayar A . Properties of external plexiform layer interneurons in mouse olfactory bulb slices . Neuroscience . 2005 ; 133 : 819 - 29 .

Chuah MI , Schwob JE , Farbman AI . Developmental anatomy of the olfactory system . In: RL Doty , editor . Handbook of olfaction and gustation . New York, NY : Marcel Dekker ; 2003 .p. 115 - 138 .

Shepherd GM . Synaptic organization of the mammalian olfactory bulb . Physiol Rev . 1972 ; 52 : 864 - 917 .

Mori K , Takahashi YK , Igarashi KM , Yamaguchi M . Maps of odorant molecular features in the Mammalian olfactory bulb . Physiol Rev . 2006 ; 86 : 409 - 33 .

Powell TP , Cowan WM , Raisman G . The central olfactory connexions . J Anat . 1965 ; 99 : 791 - 813 .

Royet JP , Plailly J . Lateralization of olfactory processes . Chem Senses . 2004 ; 29 : 731 - 45 .

Howard JD , Plailly J , Grueschow M , Haynes JD , Gottfried JA . Odor quality coding and categorization in human posterior piriform cortex . Nat Neurosci . 2009 ; 12 : 932 - 8 .

Kadohisa M . Effects of odor on emotion, with implications . Front Syst Neurosci . 2013 ; 7 : 66 .

Rolls ET . A computational theory of episodic memory formation in the hippocampus . Behav Brain Res . 2010 ; 215 : 180 - 96 .

Rolls ET . Taste, olfactory and food texture reward processing in the brain and the control of appetite . Proc Nutr Soc . 2012 ; 71 : 488 - 501 .

Zhou W , Chen D . Binaral rivalry between the nostrils and in the cortex . Curr Biol . 2009 ; 19 : 1561 - 5 .

Manual UAF . Psychological operations techniques and procedures . Psychological Operations. U.S. Army Field Manual FM 33-1-1 . 1994 .

Lin SH , Chu ST , Yuan BC , Shu CH . Survey of the frequency of olfactory dysfunction in Taiwan . J Chin Med Assoc . 2009 ; 72 : 68 - 71 .

Ruff RL , Riechers 2nd RG , Wang XF , Piero T , Ruff SS . A case-control study examining whether neurological deficits and PTSD in combat veterans are related to episodes of mild TBI . BMJ Open . 2012 ; 2 : e000312 .

Doty RL . Olfaction and multiple chemical sensitivity . Toxicol Ind Health . 1994 ; 10 : 359 - 68 .

Hill JWJW , Petrucci RHRH . General chemistry : an integrated approach . 2nd ed . Upper Saddle River, New Jersey, USA : Prentice Hall ; 1999 .

Kuehn M , Welsch H , Zahnert T , Hummel T . Changes of pressure and humidity affect olfactory function . Eur Arch Otorhinolaryngol . 2008 ; 265 : 299 - 302 .

Halar EM , DeLisa JA , Brozovich FV . Nerve conduction velocity: relationship of skin, subcutaneous and intramuscular temperatures . Arch Phys Med Rehabil . 1980 ; 61 : 199 - 203 .

Franklin TB , Krueger-Naug AM , Clarke DB , Arrigo AP , Currie RW . The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system . Int J Hyperthermia . 2005 ; 21 : 379 - 92 .

Minic J , Persuy MA , Godel E , Aioun J , Connerton I , Salesse R , et al . Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening . FEBS J . 2005 ; 272 : 524 - 37 .

Letowski TR . Owning the environment: Stealth soldier-research outline . DTIC Document . 2012 .

Headquarters, department of the army . FM 3-05.301 (FM 33-1-1) MCRP 3-40.6A Psychological operations tactics. techniques, and procedures . Accessed 31 Dec. 2003 . https://fas.org/irp/doddir/army/fm3-05-301.pdf https://fas.org/irp/doddir/army/fm3-05-301.pdf .

Beevor A . D-day: the battle for Normandy . London : Penguin ; 2009 .

Boot M . The paradox of military technology . New Atlantis . 2006 . 13 – 31 . http://www.jstor.org/stable/43152281 http://www.jstor.org/stable/43152281 .

Forette F , Seux ML , Staessen JA , Thijs L , Babarskiene MR , Babeanu S , et al . The prevention of dementia with antihypertensive treatment: new evidence from the systolic hypertension in Europe (syst-Eur) study . Arch Intern Med . 2002 ; 162 : 2046 - 52 .

Middleton LE , Yaffe K . Promising strategies for the prevention of dementia . Arch Neurol . 2009 ; 66 : 1210 - 5 .

Prince M , Bryce R , Albanese E , Wimo A , Ribeiro W , Ferri CP . The global prevalence of dementia: a systematic review and metaanalysis . Alzheimers Dement . 2013 ; 9 : 63–75. e62 .

Cain WS , Drexler M . Scope and evaluation of odor counteraction and masking . Ann N Y Acad Sci . 1974 ; 237 : 427 - 39 .

Cain WS . Odor intensity: mixtures and masking . Chem Senses . 1975 ; 1 : 339 - 52 .

Johnson LB . Odor eliminating items and methods of use for hunting . Google Patents : USA ; 2002 .

Kirk RG . In dogs we trust? Intersubjectivity, response-able relations, and the making of mine detector dogs. J Hist Behav Sci . 2014 ; 50 : 1 - 36 .

Quignon P , Kirkness E , Cadieu E , Touleimat N , Guyon R , Renier C , et al . Comparison of the canine and human olfactory receptor gene repertoires . Genome Biol . 2003 ; 4 : R80 .

Bear CaP M , Barry W , Michael A . Neuroscience: exploring the brain . USA : Lippincott Williams & Wilkins ; 2007 .

Reece WO . Functional anatomy and physiology of domestic animals . Hoboken, New Jersey, USA : Wiley ; 2009 .

Wilson AD , Baietto M . Applications and advances in electronic-nose technologies . Sens (Basel) . 2009 ; 9 : 5099 - 148 .

Johnston J , Myers LJ , Waggoner LP , Williams M . Determination of canine olfactory thesholds using operant laboratory methods. In substance identification technologies . Int Soc Opt Photonics . 1994 ; 2092 : 238 - 43 .

Thomas 3rd SW , Joly GD , Swager TM . Chemical sensors based on amplifying fluorescent conjugated polymers . Chem Rev . 2007 ; 107 : 1339 - 86 .

Pamula VK . Detection of explosives . In: Pearce CT , Schift,am SS , Nagle TH , editors . Handbook of machine olfaction: Electronic Nose Technology . Hoboken : Wiley VCH ; 2002 . p. 547 - 60 .

Kohl D , Eberheim A , Schieberle P . Detection mechanisms of smoke compounds on homogenous semiconductor sensor films . Thin Solid Films . 2005 ; 490 : 1 - 6 .

Zampolli S , Elmi I , Ahmed F , Passini M , Cardinali GC , Nicoletti S , et al . An electronic nose based on solid state sensor arrays for low-cost indoor air quality monitoring applications . Sens Actuators B . 2004 ; 101 : 39 - 46 .

Kuske M , Romain AC , Nicolas J . Microbial volatile organic compounds as indicators of fungi. Can an electronic nose detect fungi in indoor environments? Build Environ . 2005 ; 40 : 824 - 31 .

Ryan MA , Shevade AV , Zhou H , Homer ML . Polymer-carbon black composite sensors in an electronic nose for air-quality monitoring . MRS Bull . 2004 ; 29 : 714 - 9 .

Willers H , de Gijsel P , Ogink N , D’Amico A , Martinelli E , Di Natale C , et al . Monitoring of biological odour filtration in closed environments with olfactometry and an electronic nose . Water Sci Technol . 2004 ; 50 : 93 - 100 .

Blaschke M , Tille T , Robertson P , Mair S , Weimar U , Ulmer H . MEMS gassensor array for monitoring the perceived Car-cabin air quality . IEEE Sens J . 2006 ; 6 : 1298 - 308 .

Kalman EL , Winquist F , Ouml , Fvendahl A , Rudell B , Wass U . Chemical gas sensors for car exhaust and cabin air monitoring . Indoor Built Environ . 2002 ; 11 : 105 - 10 .

Catarina Bastos A , Magan N . Potential of an electronic nose for the early detection and differentiation between Streptomyces in potable water . Sens Actuators B . 2006 ; 116 : 151 - 5 .

Tuovinen K , Kolehmainen M , Paakkanen H . Determination and identification of pesticides from liquid matrices using ion mobility spectrometry . Anal Chim Acta . 2001 ; 429 : 257 - 68 .

Goschnick J , Koronczi I , Frietsch M , Kiselev I . Water pollution recognition with the electronic nose KAMINA . Sens Actuators B . 2005 ; 106 : 182 - 6 .

Bourgeois W , Gardey G , Servieres M , Stuetz RM . A chemical sensor array based system for protecting wastewater treatment plants . Sens Actuators B . 2003 ; 91 : 109 - 16 .

Stuetz RM . Non-specific monitoring to resolve intermittent pollutant problems associated with wastewater treatment and potable supply . Water Sci Technol . 2004 ; 49 : 137 - 43 .

Fitzgerald FT , Tierney Jr LM . The bedside Sherlock Holmes . West J Med . 1982 ; 137 : 169 - 75 .

Parry AD , Chadwick PR , Simon D , Oppenheim B , McCollum CN . Leg ulcer odour detection identifies beta-haemolytic streptococcal infection . J Wound Care . 1995 ; 4 : 404 - 6 .

Chaudry AN , Travers PJ , Yuenger J , Colletta L , Evans P , Zenilman JM , et al . Analysis of vaginal acetic acid in patients undergoing treatment for bacterial vaginosis . J Clin Microbiol . 2004 ; 42 : 5170 - 5 .

Hay P , Tummon A , Ogunfile M , Adebiyi A , Adefowora A . Evaluation of a novel diagnostic test for bacterial vaginosis: ‘the electronic nose’ . Int J Std Aids . 2003 ; 14 : 114 - 8 .

Chandiok S , Crawley BA , Oppenheim BA , Chadwick PR , Higgins S , Persaud KC . Screening for bacterial vaginosis: a novel application of artificial nose technology . J Clin Pathol . 1997 ; 50 : 790 - 1 .

Lai SY , Deffenderfer OF , Hanson W , Phillips MP , Thaler ER . Identification of upper respiratory bacterial pathogens with the electronic nose . Laryngoscope . 2002 ; 112 : 975 - 9 .

Shykhon ME , Morgan DW , Dutta R , Hines EL , Gardner JW . Clinical evaluation of the electronic nose in the diagnosis of ear, nose and throat infection: a preliminary study . J Laryngol Otol . 2004 ; 118 : 706 - 9 .

Fend R , Kolk AH , Bessant C , Buijtels P , Klatser PR , Woodman AC . Prospects for clinical application of electronic-nose technology to early detection of Mycobacterium tuberculosis in culture and sputum . J Clin Microbiol . 2006 ; 44 : 2039 - 45 .

Pavlou AK , Magan N , Jones JM , Brown J , Klatser P , Turner AP . Detection of Mycobacterium tuberculosis (TB) in vitro and in situ using an electronic nose in combination with a neural network system . Biosens Bioelectron . 2004 ; 20 : 538 - 44 .

Aathithan S , Plant JC , Chaudry AN , French GL . Diagnosis of bacteriuria by detection of volatile organic compounds in urine using an automated headspace analyzer with multiple conducting polymer sensors . J Clin Microbiol . 2001 ; 39 : 2590 - 3 .

Pavlou AK , Magan N , McNulty C , Jones J , Sharp D , Brown J , et al . Use of an electronic nose system for diagnoses of urinary tract infections . Biosens Bioelectron . 2002 ; 17 : 893 - 9 .

Kodogiannis V , Wadge E . The use of gas-sensor arrays to diagnose urinary tract infections . Int J Neural Syst . 2005 ; 15 : 363 - 76 .

Mohamed EI , Linder R , Perriello G , Di Daniele N , Poppl SJ , De Lorenzo A . Predicting type 2 diabetes using an electronic nose-based artificial neural network analysis . Diabetes Nutr Metab . 2002 ; 15 : 215 - 21 .

Voss A , Baier V , Reisch R , von Roda K , Elsner P , Ahlers H , et al . Smelling renal dysfunction via electronic nose . Ann Biomed Eng . 2005 ; 33 : 656 - 60 .

Fend R , Bessant C , Williams AJ , Woodman AC . Monitoring haemodialysis using electronic nose and chemometrics . Biosens Bioelectron . 2004 ; 19 : 1581 - 90 .

Mennella JA , Beauchamp GK . Maternal di et al ters the sensory qualities of human milk and the nursling’s behavior . Pediatrics . 1991 ; 88 : 737 - 44 .

Hauser GJ , Chitayat D , Berns L , Braver D , Muhlbauer B . Peculiar odours in newborns and maternal prenatal ingestion of spicy food . Eur J Pediatr . 1985 ; 144 : 403 .

Singh PB , Herbert J , Roser B , Arnott L , Tucker DK , Brown RE . Rearing rats in a germ-free environment eliminates their odors of individuality . J Chem Ecol . 1990 ; 16 : 1667 - 82 .

Abellana M , Benedi J , Sanchis V , Ramos AJ . Water activity and temperature effects on germination and growth of Eurotium amstelodami, E. chevalieri and E. herbariorum isolates from bakery products . J Appl Microbiol . 1999 ; 87 : 371 - 80 .

Keshri G , Voysey P , Magan N . Early detection of spoilage moulds in bread using volatile production patterns and quantitative enzyme assays . J Appl Microbiol . 2002 ; 92 : 165 - 72 .

Tothill I . Rapid and on-line instrumentation for food quality assurance . Amsterdam, Netherlands : Elsevier ; 2003 .

Ruiz-Capillas C , Gillyon CM , Horner WFA . Determination of different volatile base components as quality control indices in fish by official methods and flow injection analysis . J Food Biochem . 2001 ; 25 : 541 - 53 .

Duflos G , Coin VM , Cornu M , Antinelli JF , Malle P . Determination of volatile compounds to characterize fish spoilage using headspace/mass spectrometry and solid-phase microextraction/gas chromatography/mass spectrometry . J Sci Food Agric . 2006 ; 86 : 600 - 11 .

Mansur MA , Bhadra A , Takamura H , Matoba T . Volatile flavor compounds of some sea fish and prawn species . Fish Sci . 2003 ; 69 : 864 - 6 .

Huss HH . Quality and quality changes in fresh fish . Food & Agriculture Org. : Palazzo FAO, Rome, Italy ; 1995 .

Shawyer M , Pizzali AM . The use of ice on small fishing vessels . Food & Agriculture Org. : Palazzo FAO, Rome, Italy ; 2003 .

Olafsdottir G , Jonsdottir R , Lauzon HL , Luten J , Kristbergsson K . Characterization of volatile compounds in chilled cod (Gadus morhua) fillets by gas chromatography and detection of quality indicators by an electronic nose . J Agric Food Chem . 2005 ; 53 : 10140 - 7 .

Szekely CA , Breitner JC , Fitzpatrick AL , Rea TD , Psaty BM , Kuller LH , et al . NSAID use and dementia risk in the cardiovascular health study: role of APOE and NSAID type . Neurology . 2008 ; 70 : 17 - 24 .

Barnes DE , Yaffe K . The projected effect of risk factor reduction on Alzheimer’s disease prevalence . Lancet Neurol . 2011 ; 10 : 819 - 28 .

Smith WM , Davidson TM , Murphy C . Toxin-induced chemosensory dysfunction: a case series and review . Am J Rhinol Allergy . 2009 ; 23 : 578 - 81 .

Ala’Aldeen DAA . Death Clouds: Saddam Hussein’s Chemical War Against the Kurds 5/1/1991 . Accessed 12 Apr. 2008 . http://www.dlawer.net/?q=node/79 http://www.dlawer.net/?q=node/79 .

Sidell FR , Borak J . Chemical warfare agents: II. Nerve agents . Ann Emerg Med . 1992 ; 21 : 865 - 71 .

Doty RL . Neurotoxic exposure and impairment of the chemical senses of taste and smell . Handb Clin Neurol . 2015 ; 131 : 299 - 324 .

Haxel BR , Grant L , Mackay-Sim A . Olfactory dysfunction after head injury . J Head Trauma Rehabil . 2008 ; 23 : 407 - 13 .

Drummond M , Douglas J , Olver J . Anosmia after traumatic brain injury: a clinical update . Brain Impairment . 2012 ; 8 : 31 - 40 .

Doty RL , Yousem DM , Pham LT , Kreshak AA , Geckle R , Lee WW . Olfactory dysfunction in patients with head trauma . Arch Neurol . 1997 ; 54 : 1131 - 40 .

Tokuda Y , Kikuchi M , Takahashi O , Stein GH . Prehospital management of sarin nerve gas terrorism in urban settings: 10 years of progress after the Tokyo subway sarin attack . Resuscitation . 2006 ; 68 : 193 - 202 .

Kales SN , Christiani DC . Acute chemical emergencies . N Engl J Med . 2004 ; 350 : 800 - 8 .

Gottfried JA , Smith AP , Rugg MD , Dolan RJ . Remembrance of odors past: human olfactory cortex in cross-modal recognition memory . Neuron . 2004 ; 42 : 687 - 95 .

Aiken MP , Berry MJ . Posttraumatic stress disorder: possibilities for olfaction and virtual reality exposure therapy . Virtual Real . 2015 ; 19 : 95 - 109 .

Morales-Medina JC , Juarez I , Venancio-Garcia E , Cabrera SN , Menard C , Yu W , et al . Impaired structural hippocampal plasticity is associated with emotional and memory deficits in the olfactory bulbectomized rat . Neuroscience . 2013 ; 236 : 233 - 43 .

Rolls ET , Baylis LL . Gustatory, olfactory, and visual convergence within the primate orbitofrontal cortex . J Neurosci . 1994 ; 14 : 5437 - 52 .

Emmett EA . Parosmia and hyposmia induced by solvent exposure . Br J Ind Med . 1976 ; 33 : 196 - 8 .

Lesburgueres E , Gobbo OL , Alaux-Cantin S , Hambucken A , Trifilieff P , Bontempi B . Early tagging of cortical networks is required for the formation of enduring associative memory . Science . 2011 ; 331 : 924 - 8 .

Shusterman D . Review of the upper airway, including olfaction, as mediator of symptoms . Environ Health Perspect . 2002 ; 110 Suppl 4 : 649 - 53 .

Bromley SM . Smell and taste disorders: a primary care approach . Am Fam Physician . 2000 ; 61 : 427–36. 438 .

Miwa T , Furukawa M , Tsukatani T , Costanzo RM , DiNardo LJ , Reiter ER . Impact of olfactory impairment on quality of life and disability . Arch Otolaryngol Head Neck Surg . 2001 ; 127 : 497 - 503 .

Schubert CR , Cruickshanks KJ , Klein BE , Klein R , Nondahl DM . Olfactory impairment in older adults: five-year incidence and risk factors . Laryngoscope . 2011 ; 121 : 873 - 8 .

Smeets MA , Veldhuizen MG , Galle S , Gouweloos J , de Haan AM , Vernooij J , et al . Sense of smell disorder and health-related quality of life . Rehabil Psychol . 2009 ; 54 : 404 - 12 .

Schubert CR , Cruickshanks KJ , Fischer ME , Huang GH , Klein BE , Klein R , et al . Olfactory impairment in an adult population: the beaver dam offspring study . Chem Senses . 2012 ; 37 : 325 - 34 .

Alves J , Petrosyan A , Magalhaes R . Olfactory dysfunction in dementia . World J Clin Cases . 2014 ; 2 : 661 - 7 .

Karantzoulis S , Galvin JE . Distinguishing Alzheimer’s disease from other major forms of dementia . Expert Rev Neurother . 2014 ; 11 ( 11 ): 1579 - 91 .

Coleman P , Federoff H , Kurlan R . A focus on the synapse for neuroprotection in Alzheimer disease and other dementias . Neurology . 2004 ; 63 : 1155 - 62 .

Herz RS , Schankler C , Beland S . Olfaction, emotion and associative learning: effects on motivated behavior . Motiv Emotion . 2004 ; 28 : 363 - 83 .

Gates NJ , Sachdev PS , Fiatarone Singh MA , Valenzuela M . Cognitive and memory training in adults at risk of dementia: a systematic review . BMC Geriatr . 2011 ; 11 : 55 .

de la Fuente-Fernandez R . Impact of neuroprotection on incidence of Alzheimer’s disease . PLoS One . 2006 ; 1 : e52 .

Lampit A , Hallock H , Valenzuela M . Computerized cognitive training in cognitively healthy older adults: a systematic review and meta-analysis of effect modifiers . PLoS Med . 2014 ; 11 : e1001756 .

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