Association of iodized salt with goiter prevalence in Chinese populations: a continuity analysis over time

Zhen Liang; Chen Xu; Yong-Jun Luo

doi:10.1186/s40779-017-0118-5

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Association of iodized salt with goiter prevalence in Chinese populations: a continuity analysis over time

RESEARCH | Updated：2026-03-12

- Association of iodized salt with goiter prevalence in Chinese populations: a continuity analysis over time
- Military Medical Research Vol. 4, Issue 3, Pages: 149-156(2017)
- Affiliations：
  
  1.Department of Military Medical Geography, College of High Altitude Military Medicine, Third Military Medical University, Chongqing 400038, China
  2.Battalion 5 of Cadet Brigade, Third Military Medical University, Chongqing 400038, China
  3.Key Laboratory of High Altitude Medicine of PLA, Third Military Medical University, Chongqing 400038, China
- Author bio：
  
  *: ajun-333333@163.com
- Funds：
- DOI：10.1186/s40779-017-0118-5
  CLC：
- Published：2017-09
- Accepted：
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Liang et al.: Association of iodized salt with goiter prevalence in Chinese populations: a continuity analysis over time. Mil Med Res, 2017, 4: 8
DOI：

Liang et al.: Association of iodized salt with goiter prevalence in Chinese populations: a continuity analysis over time. Mil Med Res, 2017, 4: 8 DOI： 10.1186/s40779-017-0118-5.

摘要

Abstract

Background:

Iodine deficiency disorders (IDD) refer to diseases that are caused by insufficient iodine intake

and the best strategy to prevent IDD is the addition of iodine to dietary salt. Because iodine deficiency is a common cause of goiter

the prevalence as effectively controlled after the implementation of universal salt iodization (USI) in China. However

there is substantial controversy as to whether the incidence of thyroid disorders is related to iodized salt intake. Therefore

we aimed to clarify whether the risk of goiter can be promoted by USI.

Methods:

A longitudinal continuous study based on the national monitoring results of IDD in China was performed for 3 consecutive years. We recorded the following indicators of IDD from 31 provinces: goiter number

two degrees of goiter (the degree of goiter severity) and cretinism (three endemic diseases)

iodized salt intake

median urinary iodine concentration (UIC)

soil iodine content and coverage rates of iodized salt. One-way Analysis of Variance (ANOVA) and linear regression analyses examined the differences between the three groups and correlations

respectively. Data were collected from the Chinese national IDD surveillance data in 2011-2013

and the background values of Chinese soil elements were published in 1990.

Results:

A reference male’s daily intake of maximum iodine was 378.9μg

379.2μg and 366.9μg in 2011

2012

and 2013

respectively. No statistical association between daily iodized salt intake and the three endemic diseases was observed in 2011-2013 (

0.05). No association was observed between daily iodized salt intake and the UIC of children in 2011 (

0.05). Linear regression revealed no significant correlation between the soil iodine content and three endemic diseases. The present study indicated no difference in the daily iodized salt intake in each province during three years (

=0.886

=0.647). The coverage rate of iodized salt remained above 98.7%

and goiter rates were stable in 2011-2013.

Conclusion:

There was no significant association between iodized salt intake and the three endemic diseases

suggesting that the current nutrition level of iodized salt did not cause the high goiter prevalence.

关键词

Keywords

references

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