Smoking is associated with the incidence of AMS: A large-sample cohort study

Pan Song; Ji-Hang Zhang; Jun Qin; Xu-Bin Gao; Jie Yu; Xu-Gang Tang; Cai-Fa Tang; Lan Huang

doi:10.1186/2054-9369-1-16

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Smoking is associated with the incidence of AMS: A large-sample cohort study

RESEARCH | Updated：2026-03-12

- Smoking is associated with the incidence of AMS: A large-sample cohort study
- Military Medical Research Vol. 1, Issue 2, Pages: 98-102(2014)
- Affiliations：
  
  1.Institute of Cardiovascular Diseases of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, People’s Republic of China
  2.Institute of Internal Medicine-Neurology of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, People’s Republic of China
- Author bio：
  
  *: huanglan260@126.com
- Funds：
- DOI：10.1186/2054-9369-1-16
  CLC：
- Published：2014-06
- Accepted：
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Song et al.: Smoking is associated with the incidence of AMS: A large-sample cohort study. Mil Med Res 2014, 1: 16
DOI：

Song et al.: Smoking is associated with the incidence of AMS: A large-sample cohort study. Mil Med Res 2014, 1: 16 DOI： 10.1186/2054-9369-1-16.

摘要

Abstract

Background:

In recent years

the number of people visiting high altitudes has increased. After rapidly ascending to a high altitude

some of these individuals

who reside on plains or other areas of low altitude

have suffered from acute mountain sickness (AMS). Smoking interferes with the body's oxygen metabolism

but research about the relationship between smoking and AMS has yielded controversial results.

Methods:

We collected demographic data

conducted a smoking history and performed physical examinations on 2

000 potential study participants

at sea level. Blood pressure (BP) and pulse oxygen saturation (SpO

) were measured for only some of the patients due to time and manpower limitations. We ultimately recruited 520 smokers and 450 nonsmokers according to the inclusion and exclusion criteria of our study. Following acute high-altitude exposure

we examined their Lake Louise Symptom (LLS) scores

HR and SpO

; however

cerebral blood flow (CBF) was measured for only some of the subjects due to limited time

manpower and equipment.

Results:

Both the incidence of AMS and Lake Louise Symptom (LLS) scores were lower in smokers than in nonsmokers. Comparing AMS-related symptoms between nonsmokers and smokers

the incidence and severity of headaches and the incidence of sleep difficulties were lower in smokers than in nonsmokers. The incidences of both cough and mental status change were higher in smokers than in nonsmokers; blood pressure

HR and cerebral blood flow velocity were lower in smokers than in nonsmokers.

Conclusions:

Our findings suggest that the incidence of AMS is lower in the smoking group

possibly related to a retardation of cerebral blood flow and a relief of AMS-related symptoms

such as headache.

关键词

Keywords

references

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Mountain Sickness Research Institute, 18th Hospital of PLA

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