Type 2 diabetes does not inevitably shorten life expectancy

Huai-Dong Du

doi:10.1016/j.mmr.2026.100029

Your Location：

Home >

Browse articles >

Type 2 diabetes does not inevitably shorten life expectancy

COMMENTARY | Updated：2026-05-11

- Type 2 diabetes does not inevitably shorten life expectancy
- Military Medical Research (2026)
- Affiliations：
  
  Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK
- Author bio：
  
  *Huai-Dong Du, Huaidong.du@ndph.ox.ac.uk
- Funds：
- DOI：10.1016/j.mmr.2026.100029
  CLC：
- Received：23 March 2026，
  
  Accepted：26 March 2026，
  
  Published：2026-04
- Accepted：
Scan QR Code
Du HD. Type 2 diabetes does not inevitably shorten life expectancy. Mil Med Res. 2026;13(1):100029.
DOI：

Du HD. Type 2 diabetes does not inevitably shorten life expectancy. Mil Med Res. 2026;13(1):100029. DOI： 10.1016/j.mmr.2026.100029.

摘要

Abstract

关键词

Keywords

references

Bragg F , Holmes MV , Iona A , Guo Y , Du H , Chen Y , et al . Association between diabetes and cause-specific mortality in rural and urban areas of China . JAMA . 2017 ; 317 ( 3 ): 280 - 9 .

Qiu ZX , Qian F , Zhang YB , Liu J , Geng TT , Li R , et al . Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies . Mil Med Res . 2025 ; 12 ( 1 ): 89 .

Lean ME , Leslie WS , Barnes AC , Brosnahan N , Thom G , McCombie L , et al . Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial . Lancet . 2018 ; 391 ( 10120 ): 541 - 51 .

Taheri S , Zaghloul H , Chagoury O , Elhadad S , Ahmed SH , El Khatib N , et al . Effect of intensive lifestyle intervention on bodyweight and glycaemia in early type 2 diabetes (DIADEM-I): an open-label, parallel-group, randomised controlled trial . Lancet Diabetes Endocrinol . 2020 ; 8 ( 6 ): 477 - 89 .

Bhaskaran K , Dos-Santos-Silva I , Leon DA , Douglas IJ , Smeeth L . Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3.6 million adults in the UK . Lancet Diabetes Endocrinol . 2018 ; 6 ( 12 ): 944 - 53 .

Iona A , Bragg F , Guo Y , Yang L , Chen Y , Pei P , et al . Adiposity and risks of vascular and non-vascular mortality among Chinese adults with type 2 diabetes: a 10-year prospective study . BMJ Open Diabetes Res Care . 2022 ; 10 ( 1 ): e002489 .

Lean ME , Leslie WS , Barnes AC , Brosnahan N , Thom G , McCombie L , et al . 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study . Lancet Diabetes Endocrinol . 2024 ; 12 ( 4 ): 233 - 46 .

Frias JP , Davies MJ , Rosenstock J , Perez Manghi FC , Fernandez Lando L , Bergman BK , et al . Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes . N Engl J Med . 2021 ; 385 ( 6 ): 503 - 15 .

Lincoff AM , Brown-Frandsen K , Colhoun HM , Deanfield J , Emerson SS , Esbjerg S , et al . Semaglutide and cardiovascular outcomes in obesity without diabetes . N Engl J Med . 2023 ; 389 ( 24 ): 2221 - 32 .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Associations of different definitions of prediabetes and diabetes with all-cause and cause-specific mortality: a nationally representative cohort study

Risk factor control in relation to mortality and life expectancy among people with type 2 diabetes: results from 3 nationwide cohort studies

Metabolic syndrome and risk of sepsis and sepsis-related mortality: evidence from two large prospective cohort studies

Serum immunoglobulin G predicts mortality and stratifies intravenous immunoglobulin benefit in sepsis patients

Sepsis in burn care: incidence and outcomes

Related Author

Mei Zhang

Zi-Xin Qiu

Yue Wang

Xiao Zhang

Shi-Yu Zhao

Chun Li

Zhen-Ping Zhao

Shen-Han Xiang

Related Institution

National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention

Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Ministry of Education Key Laboratory of Environment and Health, and State Key Laboratory of Environment Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

Clinical Center for Human Genomic Research, Union Hospital, Huazhong University of Science and Technology

Hubei Clinical Research Center of Metabolic and Cardiovascular Disease, Huazhong University of Science and Technology

Hubei Key Laboratory of Metabolic Abnormalities and Vascular Aging, Huazhong University of Science and Technology

⁰