First imported <italic style="font-style: italic">Plasmodium ovale</italic> malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis

María Eugenia Castellanos; Sheilee Díaz; Emily Parsons; Leonard F Peruski; Fabiola Enríquez; Juan Luis Ramírez; Norma Padilla

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First imported Plasmodium ovale malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis

CASE REPORT | Updated：2026-03-12

- First imported Plasmodium ovale malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis
- Military Medical Research Vol. 1, Issue 4, Pages: 244-247(2014)
- Affiliations：
  
  1.Center for Health Studies-Universidad del Valle de Guatemala (CES-UVG). 18 Av. 11-95, zona 15, Vista Hermosa III, Guatemala, Guatemala
  2.National Reference Laboratory, Ministry of Health and Welfare. Km. 22, Carretera al Pacífico, Barcenas, Villa Nueva, Guatemala, C.A. Guatemala, Guatemala
  3.F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences. 4301 Jones Bridge Road, Bethesda, Maryland 20814, USA
  4.Global Disease Detection Program, Centers for Disease Control and Prevention (CDC), Central America Regional Office. 1600 Clifton Road NE, MS-D68, Atlanta, Georgia 30333, USA
  5.Military Healthcare and Social Services, Ministry of Defense, Guatemala, Guatemala. Finca El Palomar, Acatan, Sta. Rosita Zona 16, Guatemala, Guatemala
  6.Military Medical Center, Ministry of Defense, Guatemala, Guatemala. Finca El Palomar, Acatan, Sta. Rosita Zona 16, Guatemala, Guatemala
- Author bio：
  
  *: npadilla@ces.uvg.edu.gt
- Funds：
- DOI：
  CLC：
- Published：2014-12
- Accepted：
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Castellanos et al.: First imported Plasmodium ovale malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis. Mil Med Res 2014
DOI：

Castellanos et al.: First imported Plasmodium ovale malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis. Mil Med Res 2014 DOI：

摘要

Abstract

The Mesoamerican Ministers of Health have set 2020 as the target for malaria elimination to be achieved in the region. Imported malaria cases are a potential threat to countries attempting elimination or working to prevent resurgence. We report the first imported Plasmodium ovale infection with molecular confirmation in Central America

which occurred in a Guatemalan soldier that had been deployed in Africa. The obstacles for its diagnosis using the standard microscopy technique and the need to improve its detection are discussed.

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World Health Organization : World malaria report 2011 . Geneva : World Health Organization ; 2011 .

de Laval F , Oliver M , Rapp C , Pommier de Santi V , Mendibil A , Deparis X , Simon F : The challenge of diagnosing Plasmodium ovale malaria in travellers: report of six clustered cases in French soldiers returning from West Africa . Malaria J 2010 , 9 : 358 .

Collins WE , Jeffery GM : Plasmodium ovale: parasite and disease . Clin Microbiol Rev 2005 , 18 ( 3 ): 570 - 581 .

Mueller I , Zimmerman PA , Reeder JC : Plasmodium malariae and Plasmodium ovale--the "bashful" malaria parasites . Trends Parasitol 2007 , 23 : 278 - 283 .

Sutherland CJ , Tanomsing N , Nolder D , Oguike M , Jennison C , Pukrittayakamee S , Dolecek C , Hien TT , do Rosário VE , Arez AP , Pinto J , Michon P , Escalante AA , Nosten F , Burke M , Lee R , Blaze M , Otto TD , Barnwell JW , Pain A , Williams J , White NJ , Day NP , Snounou G , Lockhart PJ , Chiodini PL , Imwong M , Polley SD : Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally . J Infect Dis 2010 , 201 : 1544 - 1550 .

Meneses B , Blair S : Malaria por Plasmodium ovale . Acta Med Colomb 1995 , 20 : 288 - 291 .

Velázquez A , Álvarez F , Zavala C : Paludismo. Reporte de un caso y revisión de la literatura . Med Sur 2006 , 13 : 129 - 135 .

Limongi JE , Costa DC , Carvalho LH , Lopes IS , Silva AA , Ferreira MS : Plasmodium ovale malaria in Brazil: report of an imported case with a prolonged incubation period . J Infect Dev Countr 2014 , 8 : 554 - 557 .

Arevalo-Herrera M , Quiñones ML , Guerra C , Céspedes N , Giron S , Ahumada M , Piñeros JG , Padilla N , Terrientes Z , Rosas A , Padilla JC , Escalante AA , Beier JC , Herrera S : Malaria in selected non-Amazonian countries of Latin America . Acta Trop 2012 , 121 : 303 - 314 .

Dirección General de Servicios de Salud. División de Malaria de Guatemala : Memoria Anual 1977 . Guatemala : Dirección General de Servicios de Salud. División de Malaria de Guatemala , 1978 .

World Health Organization : World malaria report 2013 . Geneva : World Health Organization , 2013 .

Galappaththy GN , Fernando SD , Abeyasinghe RR : Imported malaria: a possible threat to the elimination of malaria from Sri Lanka? Trop Med Int Health 2013 , 18 : 761 - 768 .

Juliao PC , Sosa S , Gonzalez LD , Padilla N , Ortiz L , Goldman I , Udhayakumar V , Lindblade KA : Importation of chloroquine-resistant Plasmodium falciparum by Guatemalan peacekeepers returning from the Democratic Republic of the Congo . Malaria J 2013 , 12 : 344 .

Patel JC , Taylor SM , Juliao PC , Parobek CM , Janko M , Gonzalez LD , Ortiz L , Padilla N , Tshefu AK , Emch M , Udhayakumar V , Lindblade K , Meshnick SR : Genetic evidence of importation of drug-resistant plasmodium falciparum to Guatemala from the democratic republic of the Congo . Emerg Infect Dis 2014 , 20 : 932 - 940 .

Ministerio de Salud Pública y Asistencia Social de Guatemala : Normas de Atención en Salud Integral para el Primero y Segundo Nivel, 2010 . Guatemala : Ministerio de Salud Pública y Asistencia Social de Guatemala ; 2010 .

Mangold KA , Manson RU , Koay ES , Stephens L , Regner M , Thomson RB Jr , Peterson LR , Kaul KL : Real-time PCR for detection and identification of Plasmodium spp . J Clin Microbiol 2005 , 43 : 2435 - 2440 . doi: 10.1128/JCM.43.5.2435-2440.2005 http://doi.org/10.1128/JCM.43.5.2435-2440.2005 .

Snounou G , Viriyakosol S , Zhu XP , Jarra W , Pinheiro L , do Rosario VE , Thaithong S , Brown KN : High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction . Mol Biochem Parasit 1993 , 61 : 315 - 320 .

Oguike MC , Betson M , Burke M , Nolder D , Stothard JR , Kleinschmidt I , Proietti C , Bousema T , Ndounga M , Tanabe K , Ntege E , Culleton R , Sutherland CJ : Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities . Int J Parasitol 2011 , 41 : 677 - 683 .

Shaha DP , Pacha LA , Garges EC , Scoville SL , Mancuso JD : Confirmed malaria cases among Active Component U.S. Army Personnel, January-September 2012 . MSMR 2013 , 20 : 6 - 9 .

Lim YA , Mahmud R , Chew CH , TT , Chua KH : Plasmodium ovale infection in Malaysia: first imported case . Malaria J 2010 , 9 : 272 .

Obare P , Ogutu B , Adams M , Odera JS , Lilley K , Dosoo D , Adhiambo C , Owusu-Agyei S , Binka F , Wanja E , Johnson J : Misclassification of Plasmodium infections by conventional microscopy and the impact of remedial training on the proficiency of laboratory technicians in species identification . Malaria J 2013 , 12 : 113 .

World Health Organization : Global report on antimalarial drug efficacy and drug resistance: 2000-2010 . Geneva : World Health Organization ; 2010 .

Matisz CE , Naidu P , Shokoples SE , Grice D , Krinke V , Brown SZ , Kowalewska-Grochowska K , Houston S , Yanow SK : Post-arrival screening for malaria in asymptomatic refugees using real-time PCR . Am J Trop Med Hyg 2011 , 84 : 161 - 165 .

Hill DR , Baird JK , Parise ME , Lewis LS , Ryan ET , Magill AJ : Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I . Am J Trop Med Hyg 2006 , 75 : 402 - 415 .

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First imported Plasmodium ovale malaria in Central America: Case report of a Guatemalan soldier and a call to improve its accurate diagnosis

DOI：

摘要

Abstract

关键词

Keywords

references