The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum

张世民; 管惟滨; 杨志铭; 李建新; 周元昌; 魏尧梅

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The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum

Updated：2026-03-12

- The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum
- Military Medical Research Issue 2, Pages: 141-146(1987)
- Affiliations：
  
  1. Department of Biochemistry Second Military Medical College
  2. ,Shanghai
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1987
- Accepted：
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[1]张世民,管惟滨,杨志铭,李建新,周元昌,魏尧梅.The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum[J].Journal of Medical Colleges of PLA,1987(02):141-146.
DOI：

[1]张世民,管惟滨,杨志铭,李建新,周元昌,魏尧梅.The Receptor Role of Glycophorin A during the Invasion of Erythrocytes by Plasmodium Falciparum[J].Journal of Medical Colleges of PLA,1987(02):141-146. DOI：

摘要

Abstract

正

Under the condition of in vitro culture

the effects of glycophorin A（GPA）of human erythrocyte membrane

anti-GPA IgG

-acid glycoprotein

ovomucoid

wheat germ agglutinin

etc.on the invasion of erythrocytes by P.falciparum were observed in this study.The results show that the combination ofGPA with P.falciparum merozoites has high specificity

high affinity and atendency to saturation

and produces specific biological effects.These confirm forthe first time from the characteristics of the ligand-receptor interaction that GPAis a receptor recognized and bound by P.falciparum merozoites.

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