Effects of Zinc on Burns Healing and Correlation Between Serum Zinc and Serum Protein and Alkaline Phosphatase in Burned Rabbits
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Effects of Zinc on Burns Healing and Correlation Between Serum Zinc and Serum Protein and Alkaline Phosphatase in Burned Rabbits
Military Medical ResearchIssue 2, Pages: 185-190(1988)
Affiliations:
1. Department of Military Hygiene Second Military Medical College and Department of Warship Nutrition and Water Supply
2. Naval Medical Research Institute
3. ,Shanghai
Author bio:
Funds:
DOI:
CLC:
Published:1988
Accepted:
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[1]蔡东联,王德恺,李荣杰,徐庆华.Effects of Zinc on Burns Healing and Correlation Between Serum Zinc and Serum Protein and Alkaline Phosphatase in Burned Rabbits[J].Journal of Medical Colleges of PLA,1988(02):185-190.
DOI:
[1]蔡东联,王德恺,李荣杰,徐庆华.Effects of Zinc on Burns Healing and Correlation Between Serum Zinc and Serum Protein and Alkaline Phosphatase in Burned Rabbits[J].Journal of Medical Colleges of PLA,1988(02):185-190.DOI:
Effects of Zinc on Burns Healing and Correlation Between Serum Zinc and Serum Protein and Alkaline Phosphatase in Burned Rabbits
摘要
Abstract
<正> We report herein effects of varying dietary zinc contents on burns healing andcorrelation between serum zinc and serum alkaline phosphatase (AKP) activity and serumprotein in 15% total body surface area (TBSA) of Ⅲ°burned Lop rabbits.Serum zincconcentration in the rabbits given a low zinc diet for 2 weeks and those with burnsdecreased significantly
and further decreased and failed to return to normal in the rabbitwith a low zinc diet and burns.On the contrary
serum zinc was recovered rapidly tonormal in the groups fed an adequate zinc diet.Similar changes were found in serum AKPactivity.Postburn total serum protein and albumin contents were markedly decreased anddid not return to normal on d 15.Burns healing in the high zinc group was over 10 dfaster than that in the low zinc group.Serum zinc was found to be well correlated withserum AKP activity and serum protein.These results strongly suggest that zinc might be afactor benefiting burns healing.We conclude that serum AKP activity could be used as adiagnostic criterion of postburn hypozincemia as well as a valid index in the assessment ofthe effectiveness of supplemental zinc.
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