Ultrastructural Study of Nucleoli in Primary Hepatocellular Carcinoma

王文亮; 刘健; 李学荣

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Ultrastructural Study of Nucleoli in Primary Hepatocellular Carcinoma

Updated：2026-03-12

- Ultrastructural Study of Nucleoli in Primary Hepatocellular Carcinoma
- Military Medical Research Issue 4, Pages: 306-309(1987)
- Affiliations：
  
  Department of Pathology Electron Microscopy Laboratory Fourth Military Medical College Xi’an
- Author bio：
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- Published：1987
- Accepted：
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[1]王文亮,刘健,李学荣.Ultrastructural Study of Nucleoli in Primary Hepatocellular Carcinoma[J].Journal of Medical Colleges of PLA,1987(04):306-309+393-394.
DOI：

[1]王文亮,刘健,李学荣.Ultrastructural Study of Nucleoli in Primary Hepatocellular Carcinoma[J].Journal of Medical Colleges of PLA,1987(04):306-309+393-394. DOI：

摘要

Abstract

<正> The specimens of 55 cases of hepatoma were prepared with routineparaffin and ultrathin sections. Under light microscope

7 cases were gradeI hepatoma

and 38 and 10 cases were grade Ⅱ and Ⅲ

respectively.Ultrastructurally

the nucleoli were markedly enlarged

increased in numberand showed polymorphism. The more poorly differentiated hepatomasmanifested the more prominent abnormalities of the nucleoli. Thesephenomena were related closely to the vigorous metabolism of hepatoma. Onthe basis of the nucleolar changes

it might probably be regarded as one ofthe criteria for the differentiation of hepatomas and helpful to prognosis aswell.

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