Chromosome Alterations of Peripheral Lymphocytes in Patients with Cervical Cancer
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Chromosome Alterations of Peripheral Lymphocytes in Patients with Cervical Cancer
Military Medical ResearchIssue 3, Pages: 277-281(1989)
Affiliations:
Department of Obstetrics and Gynecology Xijing Hospital Fourth Military Medical University Xi’an
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Published:1989
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[1]赵海波,华钰,王荣光,张宛明,王德堂.Chromosome Alterations of Peripheral Lymphocytes in Patients with Cervical Cancer[J].Journal of Medical Colleges of PLA,1989(03):277-281.
DOI:
[1]赵海波,华钰,王荣光,张宛明,王德堂.Chromosome Alterations of Peripheral Lymphocytes in Patients with Cervical Cancer[J].Journal of Medical Colleges of PLA,1989(03):277-281.DOI:
Chromosome Alterations of Peripheral Lymphocytes in Patients with Cervical Cancer
摘要
Abstract
<正> Sister chromatid exchanged (SCE) and chromosome aberrations in peripheral lymphocytesof 30 patients with cervical cancer and relative lengths of C-band in 20 patients were studied. Verysignificant increase in SCE
hypodiploidies and relative lengths of C-band of chromosome 9 were ob-served
and significant increases in polyploidies
structural aberrations and relative lengths of C-bandof chromosome 1 were also found in cancer patients as compared with the controls
with all in non-randomized distribution. No differende was noted in alterations between stage Ⅱ and Ⅲ cancers.These findings suggest that chromosomal instability in the cervical cancer patients may represent aningerent trait in the patient and be related to the increased susceptibility of the individual to malignan-cy.
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