<正> Changes of gastro-duodenal mucosal blood flow （GDMBF） in the healingprocess of 82 patients with gastric ulcer

130 with duodenal ulcer and 9 with active ul-cer induced by gastric polypectomy were studied by endoscopic laser Doppler flowme-try.In 108 normal subjects

the mucosal blood flow at the angle and antrum of the les-ser curvature and on the anterior wall of the duodenal bulb was the smallest （P<0.01）.In patients with gastric ulcer

gastric mucosal blood flow （GMBF）significantly decrea-Sed at the active stage and increased at the healing stage （P<0.01 ）.GDMBF significan-tly increased （P<0.01） at the active stage and returned to normal at the healing stage ofduodenal ulcer.GDMBF was unchanged in the healing process of the active ulcer inducedby gastric polypectomy.The mucosal blood flow at ulcer centre and margins significan-tly decreased at the active stage and markedly increased at the healing stage as compa-red with that of surrounding mucosa.We conclude that GMBF plays an importantrole in the developing and healing process of peptic ulcers.