Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma

杨甲梅; 吴孟超; 陈汉

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Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma

Updated：2026-03-12

- Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma
- Military Medical Research Issue 1, Pages: 21-24(1989)
- Affiliations：
  
  Institute of Hepatobiliary Surgery Changhai Hospital Second Military Medical University Shanghai
- Author bio：
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- Published：1989
- Accepted：
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[1]杨甲梅,吴孟超,陈汉.Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J].Journal of Medical Colleges of PLA,1989(01):21-24.
DOI：

[1]杨甲梅,吴孟超,陈汉.Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J].Journal of Medical Colleges of PLA,1989(01):21-24. DOI：

摘要

Abstract

<正> α-L-fucosidasc （AFU） activity was determined by referring to Troost’s method in sera

liv-er tissues and lesions from patients with hepatoccllular carcinoma （HCC）

other liverspace-occupying lesions （SOL） and diseases. The results showed that the sensitivity and specificityfor the diagnosis of HCC were 81.2% and 83. 3% respectively with the assay of serum AFU activi-ty

and sensitivities in the diagnosis of AFP-negative and early HCC were 76.1% and 70. 8%

respectively. The AFU activity in the HCC tissues and their pericancerous liver tissues was twice asmuch as controls

and consisted with their serum AFU activity （r=0. 742

P<0.01）. It is sug-gested that AFU could be a new biologic marker of HCC and have an important value in thediagnosis of HCC.

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