Effect of Microiontophoretically Applied Cyproheptadine on the Nociceptive Unit Discharge in the Nucleus Parafascicularis of Thalamus

佟振清; 陈水村

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Effect of Microiontophoretically Applied Cyproheptadine on the Nociceptive Unit Discharge in the Nucleus Parafascicularis of Thalamus

Updated：2026-03-12

- Effect of Microiontophoretically Applied Cyproheptadine on the Nociceptive Unit Discharge in the Nucleus Parafascicularis of Thalamus
- Military Medical Research Issue 3, Pages: 229-232(1989)
- Affiliations：
  
  Department of Physiology First Military Medical University Guangzhou
- Author bio：
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- DOI：
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- Published：1989
- Accepted：
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[1]佟振清,陈水村.Effect of Microiontophoretically Applied Cyproheptadine on the Nociceptive Unit Discharge in the Nucleus Parafascicularis of Thalamus[J].Journal of Medical Colleges of PLA,1989(03):229-232.
DOI：

[1]佟振清,陈水村.Effect of Microiontophoretically Applied Cyproheptadine on the Nociceptive Unit Discharge in the Nucleus Parafascicularis of Thalamus[J].Journal of Medical Colleges of PLA,1989(03):229-232. DOI：

摘要

Abstract

<正> Experiments were performed on 25 rats. Putative serotonergic antagonist

Cyproheptadine（Cyp）

was applied microiontophoretically on the nucleus parafascicularis of the thalamus （Pf） andthe effect of Cyp on Pf nociceptive neuronal discharge was observed. The result suggested that Cypcan increase the spontaneous and evoked discharge rates of Pf nociceptive neuron

and that Cypmay antagonize the inhibitory effect of endogenous serotonin on the spontaneous and evokeddischarges of Pf nociceptive neurons.

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