Protection of retina from lipid peroxidation with super’oxide dismutase

徐度; 蔡用舒; 惠延年; 莫简; 孙淑芬; 王多宁

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Protection of retina from lipid peroxidation with super’oxide dismutase

Updated：2026-03-12

- Protection of retina from lipid peroxidation with super’oxide dismutase
- Military Medical Research Issue 2, Pages: 186-188(1991)
- Affiliations：
  
  1. Departments of Ophthalmology and Chemistry Fourth Military Medical University
  2. ,Xi’an,710032
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1991
- Accepted：
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[1]徐度,蔡用舒,惠延年,莫简,孙淑芬,王多宁.Protection of retina from lipid peroxidation with super'oxide dismutase[J].Journal of Medical Colleges of PLA,1991(02):186-188.
DOI：

[1]徐度,蔡用舒,惠延年,莫简,孙淑芬,王多宁.Protection of retina from lipid peroxidation with super'oxide dismutase[J].Journal of Medical Colleges of PLA,1991(02):186-188. DOI：

摘要

Abstract

<正> Our previous experiments demonstrated the occurrence of retinal lipidperioxidation following vitreous hemorrhage.In the present study

0.2ml ofautologous whole blood was injected into the vitreous of both eyes in rabbits.One eye of each rabbit received an additional injection of 0.2ml of superoxidedismutase （SOD

794 U）;the other eye served as a control.The malondialdehyde（MDA） in the retina was assayed with fluorescence spectrophotometry.The resultsshowed that the MDA was significantly lower in eyes injected with SOD （0.047±0.010 nmol/mg） than in control eyes （0.096±0.011 nmol/mg

P<0.05） 10d afterinjection.Ultrastructural examination revealed that the photoreceptor cells of theeyes with SOD injection were relatively normal.It is suggested that SOD can pro-tect the retina from lipid peroxidation.

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