Detrimental Effect of Free Radicals on Tissues in Rat with Burn Shock

吴坤莹; 赵克森; 朱佐江; 黄绪亮; 孟庆礼; 杨红

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Detrimental Effect of Free Radicals on Tissues in Rat with Burn Shock

Updated：2026-03-12

- Detrimental Effect of Free Radicals on Tissues in Rat with Burn Shock
- Military Medical Research Issue 2, Pages: 108-110(1989)
- Affiliations：
  
  1. Department of Pathophysiology First Military Medical University
  2. ,Guangzhou
  3. Central Laboratory
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1989
- Accepted：
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[1]吴坤莹,赵克森,朱佐江,黄绪亮,孟庆礼,杨红.Detrimental Effect of Free Radicals on Tissues in Rat with Burn Shock[J].Journal of Medical Colleges of PLA,1989(02):108-110.
DOI：

[1]吴坤莹,赵克森,朱佐江,黄绪亮,孟庆礼,杨红.Detrimental Effect of Free Radicals on Tissues in Rat with Burn Shock[J].Journal of Medical Colleges of PLA,1989(02):108-110. DOI：

摘要

Abstract

<正> A model of burn shock was reproduced in rats and the changes of water content andmalondialdehyde（MDA）concentration in tissues were measured.The results showed that there wasa significant increase of MDA concentration and water content in lung and bumed skin post burnand a positive correlation was found between MDA level and water content.Pretreatment withsuperoxide dismutase（SOD）prevented effectively lung and skin from edema.The role of oxygen freeradicals in vascular permeability disturbance and development of edema in burns was discussed.

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