Relation of predictive value to sensitivity and specificity of a diagnostic test

陈平雁; 赵小里; 俞守义; 陈清

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Relation of predictive value to sensitivity and specificity of a diagnostic test

Updated：2026-03-12

- Relation of predictive value to sensitivity and specificity of a diagnostic test
- Military Medical Research Issue 2, Pages: 197-200(1993)
- Affiliations：
  
  1. Departments of Medical Statistics’ First Military Medical University
  2. ,Guangzhou,510515
  3. Epidemiology
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1993
- Accepted：
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[1]陈平雁,赵小里,俞守义,陈清.Relation of predictive value to sensitivity and specificity of a diagnostic test[J].Journal of Medical Colleges of PLA,1993(02):197-200.
DOI：

[1]陈平雁,赵小里,俞守义,陈清.Relation of predictive value to sensitivity and specificity of a diagnostic test[J].Journal of Medical Colleges of PLA,1993(02):197-200. DOI：

摘要

Abstract

<正> This paper discusses how the positive and negative predictive values vary withcontrary variations of sensitivity and specificity at a certain disease prevalence.Let thesensitiviy be Se and the specificity be Sp at the initial cutoff point

correspondingly Se’and Sp’ at a new cutoff point:A=Se’/Se:B-（1-Sp’）/（1-Sp）:C=Sp’/Sp;D=（I-Se’）/（I-Se）.Moving the cutoff point from the initial point to the new point

if the contrary variationsof the sensitivity and specificity satisfy the inequality A>B

then the positive predictivevalue increases

otherwise it decreases or remains unchanged.If the variations satisfy theinequality C>D

then the negative prcdictive value increases

otherwise it decreasses or re-mains unchanged.

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