Preliminary observation on treatment of patients with Japanese B encephalitis with monoclonal antibody

马文煜; 姜绍谆; 张明杰; 于碧云; 黄庆生; 汪美先

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Preliminary observation on treatment of patients with Japanese B encephalitis with monoclonal antibody

Updated：2026-03-12

- Preliminary observation on treatment of patients with Japanese B encephalitis with monoclonal antibody
- Military Medical Research Issue 3, Pages: 299-302(1992)
- Affiliations：
  
  1. Department
  2. Department of Microbiology
  3. Fourth Military Medical University
  4. ,Xi’an,710032
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1992
- Accepted：
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[1]马文煜,姜绍谆,张明杰,于碧云,黄庆生,汪美先.Preliminary observation on treatment of patients with Japanese B encephalitis with monoclonal antibody[J].Journal of Medical Colleges of PLA,1992(03):299-302.
DOI：

[1]马文煜,姜绍谆,张明杰,于碧云,黄庆生,汪美先.Preliminary observation on treatment of patients with Japanese B encephalitis with monoclonal antibody[J].Journal of Medical Colleges of PLA,1992(03):299-302. DOI：

摘要

Abstract

<正> The monoclonat antibodies（McAbs）against Japanese B encephalitis virus for clinicaluse were prepared according to the standards of Food and Drug Administration（FDA

USA）.Immediately after the diagnosis

the patients were given 10 mg of McAbs（IgG）in normal salineby intravenous drip plus intramuscular injection.The average febrifugal days of the McAb treat-ment group（55 cases）

symptomatic treatment group（12 cases）

ribavirin treatment group（17cases）and thymus peptides treatment group（7 cases）were 2.86

6.20

7.16 and 9.11d

respec-tively（P<0.05 or P<0.01）.It is necessary to take the skin test before use of the McAbs andto give dexamethasone during the McAb treatment.

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