Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation

李晓军; 武建国

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Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation

Updated：2026-03-12

- Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation
- Military Medical Research Issue 4, Pages: 361-364(1989)
- Affiliations：
  
  1. the Department of Clinical Immunology of General Hospital of Nanjing Command of PLA Nanjing
  2. Second Military Medical University
  3. Shanghai and Department of Clinical Immunology,200433
  4. ,Nanjing,210002
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1989
- Accepted：
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[1]李晓军,武建国.Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J].Journal of Medical Colleges of PLA,1989(04):361-364.
DOI：

[1]李晓军,武建国.Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J].Journal of Medical Colleges of PLA,1989(04):361-364. DOI：

摘要

Abstract

正

Solid Phase enzyme-linked Immunosorbent assay（ELISA） for detectingclass-specific rheumatoid factor （RF） was established.Aggregated rabbit lgG was used ascoating antigen and the presence of RF was demonstrated by F（ab’）

fragment of anti-humanIg conjugated to horseradish peroxidase（HRP）.The results showed that high levels ofIgM-RF

IgG-RF and IgA-RF were found in patients with rheumatoid arthritis.A positive cor-relation existed between IgM-

IgG-

IgA-RF and disease activity.The presence of vasculitis al-so correlated positively with the levels of 3 class-specific RFs.

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